SCHEMBL15933601

SCHEMBL15933601

Cc1cc(N)c(SCCO)c(N)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.41
ALDH1A1 P00352 5/20 0.39
KDM4E B2RXH2 3/20 0.39
GAA P10253 2/20 0.39
ALOX15 P16050 2/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
HSD17B10 Q99714 1/20 0.39
CA2 P00918 3/20 0.34
CA12 O43570 2/20 0.34
CA1 P00915 2/20 0.34
CA7 P43166 2/20 0.34
CA13 Q8N1Q1 2/20 0.34
CA3 P07451 1/20 0.34
CA4 P22748 1/20 0.34
CA6 P23280 1/20 0.34
CA5A P35218 1/20 0.34
CA9 Q16790 1/20 0.34
CA14 Q9ULX7 1/20 0.34
CA5B Q9Y2D0 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7350416 0.83 SMN1; SMN2 (0.44) SMN1; SMN2ALDH1A1KDM4ELMNAMAPT
SCHEMBL8285547 0.75 NPC1 (0.50) SMN1; SMN2ALDH1A1ALOX15HSD17B10CA2
SCHEMBL15933600 0.74 SMN1; SMN2 (0.50) SMN1; SMN2ALDH1A1KDM4EALOX15LMNA
SCHEMBL11097118 0.71 CYP1A2 (0.41) SMN1; SMN2ALDH1A1KDM4EGAAALOX15
SCHEMBL8674326 0.67 ALDH1A1 (0.43) SMN1; SMN2ALDH1A1KDM4EGAAALOX15
SCHEMBL8536593 0.67 CA2 (0.40) SMN1; SMN2ALDH1A1KDM4ELMNAMAPT
Hydrochloric Acid SCHEMBL8671244 0.66 ALDH1A1 (0.41) SMN1; SMN2ALDH1A1KDM4EGAAALOX15
SCHEMBL18634653 0.65 ALDH1A1 (0.52) SMN1; SMN2ALDH1A1KDM4EGAAALOX15
SCHEMBL11338980 0.65 SCN4A (0.46) SMN1; SMN2ALDH1A1KDM4ELMNAMAPT
SCHEMBL23482211 0.64 KDM4E (0.44) ALDH1A1KDM4EGAALMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2950773-B1 DYE COMPOSITION USING AT LEAST ONE COUPLER OF META-PHENYLENEDIAMINE TYPE SUBSTITUTED IN POSITION 2 IN A MEDIUM COMPRISING A FATTY SUBSTANCE, PROCESSES AND DEVICE OREAL (FR) 2019-03-13 EP claimed
EP-2950773-B1 DYE COMPOSITION USING AT LEAST ONE COUPLER OF META-PHENYLENEDIAMINE TYPE SUBSTITUTED IN POSITION 2 IN A MEDIUM COMPRISING A FATTY SUBSTANCE, PROCESSES AND DEVICE OREAL (FR) 2019-03-13 EP disclosed
EP-2950773-B1 DYE COMPOSITION USING AT LEAST ONE COUPLER OF META-PHENYLENEDIAMINE TYPE SUBSTITUTED IN POSITION 2 IN A MEDIUM COMPRISING A FATTY SUBSTANCE, PROCESSES AND DEVICE OREAL (FR) 2019-03-13 EP disclosed
US-9585824-B2 Dye composition using at least one coupler of meta-phenylenediamine type substituted in position 2 in a medium comprising a fatty substance, processes and device L'OREAL (FR) 2017-03-07 US disclosed
US-9585824-B2 Dye composition using at least one coupler of meta-phenylenediamine type substituted in position 2 in a medium comprising a fatty substance, processes and device L'OREAL (FR) 2017-03-07 US disclosed
US-20150374601-A1 DYE COMPOSITION USING AT LEAST ONE COUPLER OF META-PHENYLENEDIAMINE TYPE SUBSTITUTED IN POSITION 2 IN A MEDIUM COMPRISING A FATTY SUBSTANCE, PROCESSES AND DEVICE L'OREAL (FR) 2015-12-31 US disclosed
US-20150374601-A1 DYE COMPOSITION USING AT LEAST ONE COUPLER OF META-PHENYLENEDIAMINE TYPE SUBSTITUTED IN POSITION 2 IN A MEDIUM COMPRISING A FATTY SUBSTANCE, PROCESSES AND DEVICE L'OREAL (FR) 2015-12-31 US disclosed
WO-2014118234-A2 DYE COMPOSITION USING AT LEAST ONE COUPLER OF META-PHENYLENEDIAMINE TYPE SUBSTITUTED IN POSITION 2 IN A MEDIUM COMPRISING A FATTY SUBSTANCE, PROCESSES AND DEVICE L'OREAL (FR) 2014-08-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150374601-A1 DYE COMPOSITION USING AT LEAST ONE COUPLER OF META-PHENYLENEDIAMINE TYPE SUBSTITUTED IN POSITION 2 IN A MEDIUM COMPRISING A FATTY SUBSTANCE, PROCESSES AND DEVICE KRT18, FABP4, FABP2 SMN1; SMN2 2387/4885ALDH1A1 457/4885KDM4E 2364/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.