⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15931182 | 0.84 | GAA (0.34) | — | |
| SCHEMBL15835018 | 0.78 | GAA (0.35) | — | |
| SCHEMBL15931191 | 0.77 | EPHX1 (0.30) | — | |
| SCHEMBL18643462 | 0.77 | — | — | |
| SCHEMBL25339651 | 0.75 | LMNA (0.34) | — | |
| SCHEMBL9078126 | 0.72 | TSHR (0.30) | — | |
| SCHEMBL25227444 | 0.69 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL21200621 | 0.68 | CHRNB2 (0.44) | — | |
| SCHEMBL15453395 | 0.67 | ALDH1A1 (0.36) | — | |
| SCHEMBL25339543 | 0.66 | ALDH1A1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9802933-B2 | Fluorinated 3-(2-oxo-3-(3-arylpropyl)imidazolidin-1-yl)-3-arylpropanoic acid derivatives | SCIFLUOR LIFE SCIENCES, INC. (US) | 2017-10-31 | — | — | US | disclosed |
| US-20170291900-A1 | FLUORINATED INTEGRIN ANTAGONISTS | FELIQS CORPORATION (JP) | 2017-10-12 | — | — | US | disclosed |
| EP-2953948-B1 | FLUORINATED INTEGRIN ANTAGONISTS | SCIFLUOR LIFE SCIENCES INC (US) | 2017-09-27 | — | — | EP | disclosed |
| US-9717729-B2 | Fluorinated integrin antagonists | SCIFLUOR LIFE SCIENCES, INC. (US) | 2017-08-01 | — | — | US | disclosed |
| US-20170096427-A1 | FLUORINATED 3-(2-OXO-3-(3-ARYLPROPYL)IMIDAZOLIDIN-1-YL)-3-ARYLPROPANOIC ACID DERIVATIVES | FELIQS CORPORATION (JP) | 2017-04-06 | — | — | US | disclosed |
| US-20170071939-A1 | FLUORINATED INTEGRIN ANTAGONISTS | FELIQS CORPORATION (JP) | 2017-03-16 | — | — | US | disclosed |
| US-9593114-B2 | Fluorinated 3-(2-oxo-3-(3-arylpropyl)imidazolidin-1-yl)-3-arylpropanoic acid derivatives | SCIFLUOR LIFE SCIENCES, INC. (US) | 2017-03-14 | — | — | US | disclosed |
| US-9518053-B2 | Fluorinated integrin antagonists | SCIFLUOR LIFE SCIENCES, INC. (US) | 2016-12-13 | — | — | US | disclosed |
| US-20160130270-A1 | FLUORINATED 3-(2-OXO-3-(3-ARYLPROPYL)IMIDAZOLIDIN-1-YL)-3-ARYLPROPANOIC ACID DERIVATIVES | FELIQS CORPORATION (JP) | 2016-05-12 | — | — | US | disclosed |
| US-9266884-B2 | Fluorinated 3-(2-oxo-3-(3-arylpropyl)imidazolidin-1-y1)-3-arylpropanoic acid derivatives | SCIFLUOR LIFE SCIENCES, INC. (US) | 2016-02-23 | — | — | US | disclosed |
| US-20150057308-A1 | Fluorinated 3-(2-Oxo-3-(3-Arylpropyl)Imidazolidin-1-yl)-3-Arylpropanoic Acid Derivatives | FELIQS CORPORATION (JP) | 2015-02-26 | — | — | US | disclosed |
| US-8901144-B2 | Fluorinated 3-(2-oxo-3-(3-arylpropyl)imidazolidin-1-yl)-3-arylpropanoic acid derivatives | SCIFLUOR LIFE SCIENCES, LLC (US) | 2014-12-02 | — | — | US | disclosed |
| WO-2014124302-A1 | FLUORINATED INTEGRIN ANTAGONISTS | SCIFLUOR LIFE SCIENCES, LLC (US) | 2014-08-14 | — | — | WO | disclosed |
| US-20140221410-A1 | Fluorinated 3-(2-Oxo-3-(3-Arylpropyl)Imidazolidin-1-yl)-3-Arylpropanoic Acid Derivatives | SCIFLUOR LIFE SCIENCES, LLC (US) | 2014-08-07 | — | — | US | disclosed |