Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24687543 | 0.78 | AR (0.46) | ARALDH1A1TSHRCRHR1HSD17B10 | |
| SCHEMBL1039397 | 0.76 | AR (0.45) | ARPDK2ALDH1A1TSHRCRHR1 | |
| SCHEMBL26020164 | 0.76 | AR (0.45) | ARPDK2ALDH1A1TSHRCRHR1 | |
| SCHEMBL1040705 | 0.76 | AR (0.45) | ARPDK2ALDH1A1TSHRCRHR1 | |
| SCHEMBL22897745 | 0.76 | AR (0.45) | ARPDK2ALDH1A1TSHRCRHR1 | |
| SCHEMBL13990192 | 0.75 | TSHR (0.48) | ARPDK2ALDH1A1TSHRCRHR1 | |
| SCHEMBL18517389 | 0.73 | AR (0.46) | ARPDK2ALDH1A1TSHRCRHR1 | |
| SCHEMBL13763445 | 0.73 | CRHR1 (0.48) | ARPDK2ALDH1A1TSHRCRHR1 | |
| SCHEMBL25540950 | 0.73 | ALDH1A1 (0.59) | ALDH1A1TSHRHSD17B10ALOX15MAOA | |
| SCHEMBL1040238 | 0.73 | AR (0.43) | ARPDK2ALDH1A1TSHRCRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014118093-A2 | DYE COMPOSITION COMPRISING AT LEAST ONE PARTICULAR LIPOPHILIC META-AMINOPHENOL COUPLER IN A MEDIUM RICH IN FATTY SUBSTANCES, PROCESSES AND DEVICES | L'OREAL (FR) | 2014-08-07 | — | — | WO | disclosed |