Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | THRB | P10828 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | RGS12 | O14924 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | APEX1 | P27695 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31572011 | 0.80 | TDP1 (0.55) | ALDH1A1HSD17B10ALOX15KDM4ETHRB | |
| SCHEMBL172750 | 0.80 | TDP1 (0.52) | ALDH1A1HSD17B10ALOX15KDM4ETHRB | |
| SCHEMBL1598733 | 0.80 | TSHR (0.48) | ALDH1A1HSD17B10ALOX15KDM4ETHRB | |
| SCHEMBL9230516 | 0.80 | APP (0.50) | ALDH1A1HSD17B10ALOX15KDM4ETHRB | |
| SCHEMBL4678566 | 0.78 | ALDH1A1 (0.45) | ALDH1A1HSD17B10ALOX15KDM4ETHRB | |
| SCHEMBL15934247 | 0.78 | CA3 (0.50) | ALDH1A1HSD17B10ALOX15KDM4ETHRB | |
| SCHEMBL62465 | 0.78 | ALOX15 (0.50) | ALDH1A1HSD17B10ALOX15KDM4ETHRB | |
| SCHEMBL11441737 | 0.78 | ALDH1A1 (0.50) | ALDH1A1HSD17B10ALOX15KDM4ETHRB | |
| SCHEMBL3212678 | 0.78 | HSD17B10 (0.50) | ALDH1A1HSD17B10ALOX15KDM4ETHRB | |
| SCHEMBL13922319 | 0.78 | ALDH1A1 (0.52) | ALDH1A1HSD17B10ALOX15KDM4ETHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119285571-A | Oxo-phenothiazine salt compound and preparation method and application thereof | 南京鼓楼医院 | 2025-01-10 | — | — | CN | claimed |
| CN-119285571-A | Oxo-phenothiazine salt compound and preparation method and application thereof | 南京鼓楼医院 | 2025-01-10 | — | — | CN | disclosed |
| EP-3596067-B1 | PYRAZOLE DERIVATIVES FOR THE TREATMENT OF CYSTIC FIBROSIS | FONDAZIONE ST ITALIANO TECNOLOGIA (IT) | 2023-06-07 | — | — | EP | disclosed |