Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27213513 | 0.84 | MAPT (0.46) | MAPTALDH1A1NPC1RAB9AGMNN | |
| SCHEMBL816372 | 0.84 | MAPT (0.52) | MAPTALDH1A1NPC1RAB9AGMNN | |
| SCHEMBL816836 | 0.84 | AURKA (0.44) | MAPTAURKATPX2GPR84RAB9A | |
| SCHEMBL24445859 | 0.84 | AURKA (0.44) | MAPTAURKATPX2GPR84GPR3 | |
| SCHEMBL15934242 | 0.81 | GABRA1 (0.34) | MAPTALDH1A1CYP3A4CA12CA1 | |
| SCHEMBL30695905 | 0.77 | MAPT (0.41) | MAPTALDH1A1NPC1RAB9AGMNN | |
| SCHEMBL17893665 | 0.77 | MAPT (0.41) | MAPTALDH1A1NPC1RAB9AGMNN | |
| SCHEMBL26068821 | 0.76 | TRPV1 (0.38) | MAPTALDH1A1NPC1RAB9AGMNN | |
| SCHEMBL17203809 | 0.75 | WDR5 (0.39) | MAPTALDH1A1AURKATPX2GPR84 | |
| SCHEMBL20962938 | 0.75 | ALDH1A1 (0.48) | ALDH1A1AURKATPX2GPR84SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014118093-A2 | DYE COMPOSITION COMPRISING AT LEAST ONE PARTICULAR LIPOPHILIC META-AMINOPHENOL COUPLER IN A MEDIUM RICH IN FATTY SUBSTANCES, PROCESSES AND DEVICES | L'OREAL (FR) | 2014-08-07 | — | — | WO | disclosed |