Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 7/20 | 1.00 |
| ▸ | SHBG | P04278 | 4/20 | 1.00 |
| ▸ | SERPINA6 | P08185 | 4/20 | 1.00 |
| ▸ | PRKAA2 | P54646 | 1/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.77 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.77 |
| ▸ | LMNA | P02545 | 4/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.77 |
| ▸ | MAPT | P10636 | 3/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.77 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.77 |
| ▸ | BLM | P54132 | 1/20 | 0.77 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.77 |
| ▸ | TSHR | P16473 | 1/20 | 0.77 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.77 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.77 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.77 |
| ▸ | THPO | P40225 | 1/20 | 0.77 |
| ▸ | MTOR | P42345 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aldosterone SCHEMBL19327156 | 1.00 | NR3C2 (1.00) | NR3C2SHBGSERPINA6PRKAA2SMN1; SMN2 | |
| Aldosterone SCHEMBL7191919 | 1.00 | NR3C2 (1.00) | NR3C2SHBGSERPINA6PRKAA2SMN1; SMN2 | |
| Aldosterone SCHEMBL21950215 | 1.00 | NR3C2 (1.00) | NR3C2SHBGSERPINA6PRKAA2SMN1; SMN2 | |
| Aldosterone SCHEMBL600774 | 1.00 | NR3C2 (1.00) | NR3C2SHBGSERPINA6PRKAA2SMN1; SMN2 | |
| Aldosterone SCHEMBL1675 | 1.00 | NR3C2 (1.00) | NR3C2SHBGSERPINA6PRKAA2SMN1; SMN2 | |
| Aldosterone SCHEMBL14373307 | 1.00 | NR3C2 (1.00) | NR3C2SHBGSERPINA6PRKAA2SMN1; SMN2 | |
| Aldosterone SCHEMBL21267959 | 0.99 | NR3C2 (0.98) | NR3C2SHBGSERPINA6PRKAA2SMN1; SMN2 | |
| Aldosterone SCHEMBL21082811 | 0.99 | NR3C2 (0.98) | NR3C2SHBGSERPINA6PRKAA2SMN1; SMN2 | |
| Aldosterone SCHEMBL27949081 | 0.99 | NR3C2 (0.98) | NR3C2SHBGSERPINA6PRKAA2SMN1; SMN2 | |
| Aldosterone SCHEMBL7992710 | 0.97 | NR3C2 (0.94) | NR3C2SHBGSERPINA6PRKAA2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2762884-A1 | MOLECULAR TEMPLATE AND METHOD FOR PRODUCING SAME | Hitachi, Ltd. (JP) | 2014-08-06 | — | — | EP | disclosed |