Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 7/20 | 0.98 |
| ▸ | SHBG | P04278 | 4/20 | 0.98 |
| ▸ | SERPINA6 | P08185 | 4/20 | 0.98 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.98 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.76 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.76 |
| ▸ | LMNA | P02545 | 4/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.76 |
| ▸ | MAPT | P10636 | 3/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.76 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.76 |
| ▸ | BLM | P54132 | 1/20 | 0.76 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.76 |
| ▸ | TSHR | P16473 | 1/20 | 0.76 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.76 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.76 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.76 |
| ▸ | THPO | P40225 | 1/20 | 0.76 |
| ▸ | MTOR | P42345 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aldosterone SCHEMBL21950215 | 0.99 | NR3C2 (1.00) | NR3C2SHBGSERPINA6PRKAA2SMN1; SMN2 | |
| Aldosterone SCHEMBL1675 | 0.99 | NR3C2 (1.00) | NR3C2SHBGSERPINA6PRKAA2SMN1; SMN2 | |
| Aldosterone SCHEMBL7191919 | 0.99 | NR3C2 (1.00) | NR3C2SHBGSERPINA6PRKAA2SMN1; SMN2 | |
| Aldosterone SCHEMBL19327156 | 0.99 | NR3C2 (1.00) | NR3C2SHBGSERPINA6PRKAA2SMN1; SMN2 | |
| Aldosterone SCHEMBL600774 | 0.99 | NR3C2 (1.00) | NR3C2SHBGSERPINA6PRKAA2SMN1; SMN2 | |
| Aldosterone SCHEMBL14373307 | 0.99 | NR3C2 (1.00) | NR3C2SHBGSERPINA6PRKAA2SMN1; SMN2 | |
| Aldosterone SCHEMBL15935548 | 0.99 | NR3C2 (1.00) | NR3C2SHBGSERPINA6PRKAA2SMN1; SMN2 | |
| Aldosterone SCHEMBL21267959 | 0.98 | NR3C2 (0.98) | NR3C2SHBGSERPINA6PRKAA2SMN1; SMN2 | |
| Aldosterone SCHEMBL27949081 | 0.98 | NR3C2 (0.98) | NR3C2SHBGSERPINA6PRKAA2SMN1; SMN2 | |
| Aldosterone SCHEMBL11145028 | 0.96 | NR3C2 (0.94) | NR3C2SHBGSERPINA6PRKAA2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240016796-A1 | Pharmaceutical Composition Comprising Mineralocorticoid Receptor Antagonist and Use Thereof | NOVO NORDISK A/S (DK) | 2024-01-18 | — | — | US | disclosed |
| US-11806344-B2 | Pharmaceutical composition comprising mineralocorticoid receptor antagonist and use thereof | KBP BIOSCIENCES PTE. LTD. (SG) | 2023-11-07 | — | — | US | disclosed |
| EP-3517113-A1 | PHARMACEUTICAL COMPOSITION COMPRISING MINERALOCORTICOID RECEPTOR ANTAGONIST AND USE THEREOF | KBP Biosciences Co., Ltd. (CN) | 2019-07-31 | — | — | EP | disclosed |
| US-20190201390-A1 | PHARMACEUTICAL COMPOSITION COMPRISING MINERALOCORTICOID RECEPTOR ANTAGONIST AND USE THEREOF | KBP BIOSCIENCES CO., LTD. (CN) | 2019-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240016796-A1 | Pharmaceutical Composition Comprising Mineralocorticoid Receptor Antagonist and Use Thereof | NR3C2, MC2R, REN | NR3C2 1/4885SHBG 78/4885SERPINA6 89/4885 |
| US-20190201390-A1 | PHARMACEUTICAL COMPOSITION COMPRISING MINERALOCORTICOID RECEPTOR ANTAGONIST AND USE THEREOF | NR3C2, MC2R, REN | NR3C2 1/4885SHBG 78/4885SERPINA6 89/4885 |
| US-11806344-B2 | Pharmaceutical composition comprising mineralocorticoid receptor antagonist and use thereof | NR3C2, MC2R, REN | NR3C2 1/4885SHBG 78/4885SERPINA6 89/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.