Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 7/20 | 1.00 |
| ▸ | SHBG | P04278 | 4/20 | 1.00 |
| ▸ | SERPINA6 | P08185 | 4/20 | 1.00 |
| ▸ | PRKAA2 | P54646 | 1/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.77 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.77 |
| ▸ | LMNA | P02545 | 4/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.77 |
| ▸ | MAPT | P10636 | 3/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.77 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.77 |
| ▸ | BLM | P54132 | 1/20 | 0.77 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.77 |
| ▸ | TSHR | P16473 | 1/20 | 0.77 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.77 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.77 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.77 |
| ▸ | THPO | P40225 | 1/20 | 0.77 |
| ▸ | MTOR | P42345 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aldosterone SCHEMBL15935548 | 1.00 | NR3C2 (1.00) | NR3C2SHBGSERPINA6PRKAA2SMN1; SMN2 | |
| Aldosterone SCHEMBL19327156 | 1.00 | NR3C2 (1.00) | NR3C2SHBGSERPINA6PRKAA2SMN1; SMN2 | |
| Aldosterone SCHEMBL7191919 | 1.00 | NR3C2 (1.00) | NR3C2SHBGSERPINA6PRKAA2SMN1; SMN2 | |
| Aldosterone SCHEMBL21950215 | 1.00 | NR3C2 (1.00) | NR3C2SHBGSERPINA6PRKAA2SMN1; SMN2 | |
| Aldosterone SCHEMBL600774 | 1.00 | NR3C2 (1.00) | NR3C2SHBGSERPINA6PRKAA2SMN1; SMN2 | |
| Aldosterone SCHEMBL1675 | 1.00 | NR3C2 (1.00) | NR3C2SHBGSERPINA6PRKAA2SMN1; SMN2 | |
| Aldosterone SCHEMBL21267959 | 0.99 | NR3C2 (0.98) | NR3C2SHBGSERPINA6PRKAA2SMN1; SMN2 | |
| Aldosterone SCHEMBL21082811 | 0.99 | NR3C2 (0.98) | NR3C2SHBGSERPINA6PRKAA2SMN1; SMN2 | |
| Aldosterone SCHEMBL27949081 | 0.99 | NR3C2 (0.98) | NR3C2SHBGSERPINA6PRKAA2SMN1; SMN2 | |
| Aldosterone SCHEMBL7992710 | 0.97 | NR3C2 (0.94) | NR3C2SHBGSERPINA6PRKAA2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9394290-B2 | Selective CYP11B1 inhibitors for the treatment of cortisol dependent diseases | UNIVERSITAET DES SAARLANDES CAMPUS SAARBRUECKEN (DE) | 2016-07-19 | — | — | US | disclosed |
| US-20140155407-A1 | SELECTIVE CYP11B1 INHIBITORS FOR THE TREATMENT OF CORTISOL DEPENDENT DISEASES | UNIVERSITAET DES SAARLANDES (DE) | 2014-06-05 | — | — | US | disclosed |
| US-20070249571-A1 | Novel conjugate compounds and dermatological compositions thereof | TAMARKIN PHARMACEUTICALS (IL) | 2007-10-25 | — | — | US | disclosed |
| US-20070249571-A1 | Novel conjugate compounds and dermatological compositions thereof | TAMARKIN PHARMACEUTICALS (IL) | 2007-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249571-A1 | Novel conjugate compounds and dermatological compositions thereof | CYP24A1, VDR, CYP2R1 | NR3C2 165/4885SHBG 21/4885SERPINA6 132/4885 |
| US-20140155407-A1 | SELECTIVE CYP11B1 INHIBITORS FOR THE TREATMENT OF CORTISOL DEPENDENT DISEASES | HSD11B1, CYP11B1, HSD11B2 | NR3C2 16/4885SHBG 59/4885SERPINA6 81/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.