Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.40 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.40 |
| ▸ | SSU72 | Q9NP77 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CFD | P00746 | 1/20 | 0.38 |
| ▸ | F11 | P03951 | 1/20 | 0.38 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.37 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.37 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7086395 | 0.87 | KMT2A (0.38) | ACP1PTPN12PTPN13SSU72STAT3 | |
| SCHEMBL1311395 | 0.83 | ELANE (0.47) | LMNAHTTCCR5USP28USP25 | |
| SCHEMBL27529170 | 0.80 | EGFR (0.43) | FOLH1RAB9A | |
| SCHEMBL27529171 | 0.80 | EGFR (0.43) | FOLH1RAB9A | |
| SCHEMBL5707160 | 0.79 | PRMT5 (0.42) | FOLH1CCR5KMT2ARAB9A | |
| SCHEMBL30286115 | 0.79 | PRMT5 (0.42) | FOLH1CCR5KMT2ARAB9A | |
| SCHEMBL1311951 | 0.79 | PRMT5 (0.42) | FOLH1CCR5KMT2ARAB9A | |
| SCHEMBL2671449 | 0.79 | PRMT5 (0.42) | FOLH1CCR5KMT2ARAB9A | |
| SCHEMBL7693480 | 0.78 | ELANE (0.35) | STAT3LMNAHTTCCR5CA1 | |
| SCHEMBL5080739 | 0.78 | ELANE (0.35) | STAT3LMNAHTTCCR5CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2764866-A1 | Inhibitors of nedd8-activating enzyme | IP Gesellschaft für Management mbH (DE) | 2014-08-13 | — | — | EP | disclosed |