Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28036699 | 0.86 | KDM4E (0.66) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL30884503 | 0.86 | MEN1 (0.50) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL6514641 | 0.85 | MEN1 (0.43) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL28676384 | 0.84 | KDM4E (0.51) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL28678807 | 0.83 | MEN1 (0.51) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL3467180 | 0.83 | MEN1 (0.53) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL889415 | 0.83 | EGFR (0.51) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL28509775 | 0.80 | MEN1 (0.56) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL28036700 | 0.80 | ALDH1A1 (0.44) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL1366502 | 0.79 | ALDH1A1 (0.43) | MEN1KMT2AKDM4EALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2276740-B1 | IMPROVED PROCESS FOR PREPARING QUINOLINE-3-CARBOXAMIDE DERIVATIVES | ACTAVIS GROUP PCT EHF (IS) | 2014-08-13 | — | — | EP | disclosed |