Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30884503 | 0.86 | MEN1 (0.50) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL28676384 | 0.84 | KDM4E (0.51) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL15936261 | 0.83 | MEN1 (0.51) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL7600994 | 0.83 | KMT2A (0.47) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7753691 | 0.78 | AGTR1 (0.42) | MEN1KMT2AKDM4EALDH1A1FEN1 | |
| SCHEMBL7435419 | 0.77 | KDM4E (0.72) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL24054706 | 0.74 | KDM4E (0.52) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL28036700 | 0.74 | ALDH1A1 (0.44) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL29463790 | 0.73 | ALDH1A1 (0.45) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL17713228 | 0.73 | ALDH1A1 (0.45) | MEN1KMT2AKDM4EALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110041306-B | 4-hydroxy-2-quinolone-N- (4-quinazolinone) -3-carboxamide derivatives | 中国医学科学院药物研究所 | 2022-01-11 | — | — | CN | disclosed |