Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | WEE1 | P30291 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1523071 | 0.85 | KDM4E (0.52) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL15936261 | 0.85 | MEN1 (0.51) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL889415 | 0.79 | EGFR (0.51) | MEN1KMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL1523407 | 0.75 | MEN1 (0.58) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL28036699 | 0.72 | KDM4E (0.66) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL30884503 | 0.71 | MEN1 (0.50) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL1522411 | 0.71 | ALDH1A1 (0.40) | KMT2AALDH1A1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL16099904 | 0.71 | EGLN1 (0.47) | MEN1KMT2AKDM4E | |
| SCHEMBL28676384 | 0.70 | KDM4E (0.51) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL6732535 | 0.70 | HSD17B10 (0.38) | MEN1KMT2AALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050075331-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2005-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075331-A1 | Anti-infective agents | RPL35, POLI, POLRMT | MEN1 4797/4885KMT2A 4532/4885ALDH1A1 1592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.