SCHEMBL1593873

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1594389	0.89	KEAP1 (0.45)	NPC1RAB9AKEAP1NFE2L2HDAC3
	SCHEMBL1594803	0.88	KEAP1 (0.44)	NPC1RAB9AKEAP1NFE2L2HDAC3
	SCHEMBL1594273	0.87	HDAC4 (0.53)	NPC1RAB9AHDAC3HDAC4HDAC1
	SCHEMBL1594817	0.86	FYN (0.49)	NPC1RAB9AKEAP1NFE2L2HDAC3
	SCHEMBL1594138	0.85	RAB9A (0.57)	NPC1RAB9AKEAP1NFE2L2HDAC3
	SCHEMBL1594129	0.82	NPC1 (0.44)	NPC1RAB9AHDAC3HDAC4HDAC1
	SCHEMBL12589451	0.79	NPC1 (0.43)	NPC1RAB9AHDAC3HDAC4HDAC1
	SCHEMBL1593419	0.79	PTGS1 (0.62)	KEAP1NFE2L2
	SCHEMBL1594984	0.78	HDAC4 (0.53)	NPC1RAB9AHDAC3HDAC4HDAC1
	SCHEMBL1594153	0.76	NR3C2 (0.53)	NPC1RAB9AKEAP1NFE2L2FYN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.