SCHEMBL15940347

SCHEMBL15940347

c1ccc(-c2ccc(Cc3ccccc3Oc3ccccc3Cc3ccc(-c4ccccc4)cc3)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
HRH1 P35367 6/20 0.45
DRD1 P21728 5/20 0.45
DRD2 P14416 4/20 0.45
DRD4 P21917 4/20 0.45
DRD5 P21918 4/20 0.45
IDO1 P14902 2/20 0.44
AGXT P21549 2/20 0.44
TP53 P04637 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C9 P11712 1/20 0.44
TSHR P16473 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
TAAR1 Q96RJ0 1/20 0.43
LTA4H P09960 1/20 0.43
DRD3 P35462 4/20 0.42
LMNA P02545 1/20 0.42
HTR2A P28223 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL246372 0.87 HPGD (0.58) HPGDSMN1; SMN2HRH1DRD1DRD2
Water SCHEMBL28646770 0.85 HPGD (0.56) HPGDSMN1; SMN2HRH1DRD1DRD2
SCHEMBL27462498 0.85 LTA4H (0.58) HPGDHRH1DRD1DRD2DRD4
SCHEMBL17644776 0.82 SLC5A1 (0.48) HPGDSMN1; SMN2HRH1DRD1DRD2
SCHEMBL15940350 0.81 SLC6A9 (0.52) HPGDAGXTTP53HTR2ASLC6A4
SCHEMBL17644773 0.80 SLC6A4 (0.53) HPGDSMN1; SMN2HRH1HTR2ASLC6A4
SCHEMBL9234711 0.80 SLC6A4 (0.50) HPGDSMN1; SMN2HRH1DRD1DRD2
SCHEMBL11217522 0.80 KEAP1 (0.62) HPGDSMN1; SMN2HRH1DRD1DRD2
SCHEMBL28180000 0.78 HRH1 (0.58) HPGDSMN1; SMN2HRH1DRD1DRD2
SCHEMBL5284234 0.77 LTA4H (0.60) HPGDCYP1A2CYP2C9TSHRL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8815000-B1 Solid inks comprising liquid crystalline materials XEROX CORPORATION (US) 2014-08-26 US claimed
US-20140225956-A1 SOLID INKS COMPRISING LIQUID CRYSTALLINE MATERIALS XEROX CORPORATION (US) 2014-08-14 US claimed
US-8815000-B1 Solid inks comprising liquid crystalline materials XEROX CORPORATION (US) 2014-08-26 US disclosed
US-20140225956-A1 SOLID INKS COMPRISING LIQUID CRYSTALLINE MATERIALS XEROX CORPORATION (US) 2014-08-14 US disclosed