SCHEMBL15940964

SCHEMBL15940964

CC(C)(O)C(=O)c1ccc(OCCOCCOCCOCCI)cc1

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RARB P10826 1/20 0.46
MAPT P10636 4/20 0.45
L3MBTL1 Q9Y468 2/20 0.42
PKM P14618 1/20 0.41
GAA P10253 1/20 0.41
RAB9A P51151 1/20 0.41
THRA P10827 1/20 0.41
ALDH1A1 P00352 1/20 0.40
PARP10 Q53GL7 1/20 0.40
PPARA Q07869 1/20 0.39
MAPK1 P28482 1/20 0.38
TP53 P04637 1/20 0.38
TSHR P16473 1/20 0.38
PLK1 P53350 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19860005 0.89 RARB (0.47) RARBMAPTL3MBTL1PKMGAA
SCHEMBL17921588 0.87 APP (0.47) RARBMAPTL3MBTL1PKMGAA
SCHEMBL19077766 0.87 APP (0.47) RARBMAPTL3MBTL1PKMGAA
SCHEMBL19077767 0.87 APP (0.47) RARBMAPTL3MBTL1PKMGAA
SCHEMBL316964 0.87 APP (0.47) RARBMAPTL3MBTL1PKMGAA
SCHEMBL17921585 0.87 MAPT (0.50) RARBMAPTL3MBTL1PKMGAA
SCHEMBL16139896 0.87 APP (0.47) RARBMAPTL3MBTL1PKMGAA
SCHEMBL15948143 0.85 RARB (0.46) RARBMAPTL3MBTL1PKMGAA
SCHEMBL9947183 0.85 THRA (0.56) RARBMAPTL3MBTL1PKMGAA
SCHEMBL9808683 0.85 MAPT (0.47) RARBMAPTL3MBTL1PKMGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9889226-B2 Photocrosslinked hyaluronic acid derivatives, and the preparation process and use thereof FIDIA FARMACEUTICI S.P.A. (IT) 2018-02-13 US disclosed
US-9889226-B2 Photocrosslinked hyaluronic acid derivatives, and the preparation process and use thereof FIDIA FARMACEUTICI S.P.A. (IT) 2018-02-13 US disclosed
US-9889226-B2 Photocrosslinked hyaluronic acid derivatives, and the preparation process and use thereof FIDIA FARMACEUTICI S.P.A. (IT) 2018-02-13 US disclosed
EP-2953656-B1 PHOTOCROSSLINKED HYALURONIC ACID DERIVATIVES, AND THE PREPARATION PROCESS AND USE THEREOF FIDIA FARMACEUTICI (IT) 2016-11-09 EP disclosed
EP-2953656-B1 PHOTOCROSSLINKED HYALURONIC ACID DERIVATIVES, AND THE PREPARATION PROCESS AND USE THEREOF FIDIA FARMACEUTICI (IT) 2016-11-09 EP disclosed
US-20150367027-A1 PHOTOCROSSLINKED HYALURONIC ACID DERIVATIVES, AND THE PREPARATION PROCESS AND USE THEREOF FIDIA FARMACEUTICI S.P.A. (IT) 2015-12-24 US disclosed
US-20150367027-A1 PHOTOCROSSLINKED HYALURONIC ACID DERIVATIVES, AND THE PREPARATION PROCESS AND USE THEREOF FIDIA FARMACEUTICI S.P.A. (IT) 2015-12-24 US disclosed
US-20150367027-A1 PHOTOCROSSLINKED HYALURONIC ACID DERIVATIVES, AND THE PREPARATION PROCESS AND USE THEREOF FIDIA FARMACEUTICI S.P.A. (IT) 2015-12-24 US disclosed
EP-2953656-A1 PHOTOCROSSLINKED HYALURONIC ACID DERIVATIVES, AND THE PREPARATION PROCESS AND USE THEREOF Fidia Farmaceutici S.p.A. (IT) 2015-12-16 EP disclosed
WO-2014122580-A1 PHOTOCROSSLINKED HYALURONIC ACID DERIVATIVES, AND THE PREPARATION PROCESS AND USE THEREOF FIDIA FARMACEUTICI S.P.A. (IT) 2014-08-14 WO disclosed
WO-2014122580-A1 PHOTOCROSSLINKED HYALURONIC ACID DERIVATIVES, AND THE PREPARATION PROCESS AND USE THEREOF FIDIA FARMACEUTICI S.P.A. (IT) 2014-08-14 WO disclosed