SCHEMBL19860005

SCHEMBL19860005

CCC(C)(O)C(=O)c1ccc(OCCOCCOCCOCCI)cc1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RARB P10826 1/20 0.47
MAPT P10636 4/20 0.43
THRA P10827 1/20 0.42
L3MBTL1 Q9Y468 3/20 0.41
PKM P14618 1/20 0.40
GAA P10253 1/20 0.40
TP53 P04637 1/20 0.39
TSHR P16473 1/20 0.39
PLK1 P53350 1/20 0.39
RAB9A P51151 1/20 0.39
ALDH1A1 P00352 1/20 0.38
PLA2G4B P0C869 1/20 0.38
LMNA P02545 1/20 0.38
PARP10 Q53GL7 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15940964 0.89 RARB (0.46) RARBMAPTTHRAL3MBTL1PKM
SCHEMBL5419941 0.81 NR1I2 (0.56) RARBMAPTL3MBTL1GAATP53
SCHEMBL864288 0.77 L3MBTL1 (0.59) RARBMAPTTHRAL3MBTL1TSHR
SCHEMBL9947183 0.77 THRA (0.56) RARBMAPTTHRAL3MBTL1PKM
SCHEMBL19077767 0.75 APP (0.47) RARBMAPTTHRAL3MBTL1PKM
SCHEMBL16139896 0.75 APP (0.47) RARBMAPTTHRAL3MBTL1PKM
SCHEMBL316964 0.75 APP (0.47) RARBMAPTTHRAL3MBTL1PKM
SCHEMBL17921585 0.75 MAPT (0.50) RARBMAPTTHRAL3MBTL1PKM
SCHEMBL17921590 0.75 RARB (0.54) RARBMAPTTHRAL3MBTL1PKM
SCHEMBL19077766 0.75 APP (0.47) RARBMAPTTHRAL3MBTL1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9889226-B2 Photocrosslinked hyaluronic acid derivatives, and the preparation process and use thereof FIDIA FARMACEUTICI S.P.A. (IT) 2018-02-13 US disclosed