Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15942288 | 0.85 | POLB (0.32) | POLBALOX15TSHRPLK1HTT | |
| SCHEMBL15942289 | 0.85 | NPC1 (0.33) | POLBALOX15TSHRMAPTPLK1 | |
| SCHEMBL15942093 | 0.84 | ALOX15 (0.35) | POLBALOX15TSHRMAPTTP53 | |
| SCHEMBL303837 | 0.84 | POLB (0.36) | POLBTP53 | |
| SCHEMBL4683602 | 0.79 | PLK1 (0.42) | POLBALOX15TSHRMAPTHSD17B10 | |
| SCHEMBL15941528 | 0.74 | POLB (0.33) | POLBALOX15TSHRHSD17B10PLK1 | |
| SCHEMBL15941860 | 0.74 | POLB (0.33) | POLBALOX15TSHRHSD17B10PLK1 | |
| SCHEMBL15942092 | 0.74 | FPR2 (0.36) | POLBALOX15TSHRMAPTTP53 | |
| SCHEMBL18581411 | 0.73 | HDAC6 (0.46) | TSHRMAPTPLK1HTT | |
| SCHEMBL15941342 | 0.73 | POLB (0.37) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014122674-A1 | PROCESS FOR PREPARATION OF DERIVATIVES OF TETRAHYDROPHTHALIMIDE | RALLIS INDIA LIMITED (IN) | 2014-08-14 | — | — | WO | disclosed |