SCHEMBL15944254

SCHEMBL15944254

Cc1ccc(SCC(C)C2CC(=O)C(c3c(C)cc(C)cc3C)=C(O)C2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.36
MEN1 O00255 2/20 0.36
RAB9A P51151 3/20 0.32
NPC1 O15118 2/20 0.32
HPGD P15428 3/20 0.31
USP2 O75604 1/20 0.31
NR3C1 P04150 1/20 0.31
PGR P06401 1/20 0.31
NR3C2 P08235 1/20 0.31
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
POLB P06746 1/20 0.30
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30
THRB P10828 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
EPHX2 P34913 1/20 0.30
CRBN Q96SW2 1/20 0.30
TP53 P04637 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17169157 0.93 MEN1 (0.33) KMT2AMEN1MAPTL3MBTL1
SCHEMBL17122184 0.93 NR3C1 (0.31) KMT2AMEN1RAB9ANPC1NR3C1
SCHEMBL17169167 0.92 KMT2A (0.34) KMT2AMEN1HPGDUSP2
SCHEMBL17169153 0.91 TBXA2R (0.35) KMT2AMEN1RAB9ANPC1HPGD
SCHEMBL14234219 0.91 PPARD (0.36) NR3C1PGRNR3C2
SCHEMBL17169165 0.90 MEN1 (0.31) KMT2AMEN1
SCHEMBL17169154 0.90 MEN1 (0.31) KMT2AMEN1RAB9ANPC1
SCHEMBL15944250 0.89 KMT2A (0.32) KMT2AMEN1RAB9ANPC1HPGD
SCHEMBL17122191 0.89 GRM2 (0.31)
SCHEMBL17169161 0.88 KMT2A (0.35) KMT2AMEN1RAB9ANPC1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9414588-B2 Herbicide composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-08-16 US disclosed
US-20150289505-A1 HERBICIDE COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-15 US disclosed
US-9101140-B2 Cyclohexanone compounds and herbicides comprising the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-08-11 US disclosed
US-20140228219-A1 CYCLOHEXANONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-08-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140228219-A1 CYCLOHEXANONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME CBR3, CBR1, CYP2S1 KMT2A 466/4885MEN1 4391/4885RAB9A 4307/4885
US-20150289505-A1 HERBICIDE COMPOSITION DDT, DHFR, DERL1 KMT2A 1181/4885MEN1 3856/4885RAB9A 4799/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.