SCHEMBL15944258

SCHEMBL15944258

CCc1cc(C)cc(CC)c1C1=C(O)CC(CC(C)Sc2ccc(C)cc2)CC1=O

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.30
MAPT P10636 2/20 0.30
ALDH1A1 P00352 1/20 0.30
POLB P06746 1/20 0.30
HTT P42858 1/20 0.30
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14234787 0.90 PPARD (0.31)
SCHEMBL10079458 0.86 MAPT (0.33) MAPT
SCHEMBL10079481 0.85 MAPT (0.32) MAPT
SCHEMBL10079449 0.85 MAPT (0.46) HPGDMAPTALDH1A1
SCHEMBL10079475 0.83 TSHR (0.36) MAPT
SCHEMBL15944275 0.83 CRBN (0.36) MAPTALDH1A1HTT
SCHEMBL14234190 0.81 ALDH1A1 (0.34) HPGDMAPTALDH1A1
SCHEMBL10079448 0.81 MAPT (0.31) MAPT
SCHEMBL10079440 0.80 MAPT (0.43) HPGDMAPTALDH1A1
SCHEMBL15944277 0.80 ALDH1A1 (0.34) HPGDMAPTALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9414588-B2 Herbicide composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-08-16 US disclosed
US-20150289505-A1 HERBICIDE COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-15 US disclosed
US-9101140-B2 Cyclohexanone compounds and herbicides comprising the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-08-11 US disclosed
US-20140228219-A1 CYCLOHEXANONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-08-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140228219-A1 CYCLOHEXANONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME CBR3, CBR1, CYP2S1 HPGD 1366/4885MAPT 4773/4885ALDH1A1 1329/4885
US-20150289505-A1 HERBICIDE COMPOSITION DDT, DHFR, DERL1 HPGD 585/4885MAPT 1013/4885ALDH1A1 215/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.