SCHEMBL15944310

SCHEMBL15944310

CCc1cc(C)cc(CC)c1C1=C(O)CC(C2(CS(=O)(=O)c3ccc(C)cc3)CC2)CC1=O

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14234372 0.91 BCHE (0.31)
SCHEMBL15944308 0.81
SCHEMBL15944266 0.80 ALDH1A1 (0.32) CRBNALDH1A1
SCHEMBL15944259 0.78 ALDH1A1 (0.37) CRBNALDH1A1MAPTGAA
SCHEMBL15944305 0.76 ALDH1A1 (0.36) ALDH1A1MAPT
SCHEMBL15944314 0.76 ALDH1A1 (0.40) ALDH1A1MAPT
SCHEMBL15944263 0.75
SCHEMBL10079461 0.74
SCHEMBL15945553 0.72 IDH1 (0.30)
SCHEMBL14234991 0.72 PPARD (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9414588-B2 Herbicide composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-08-16 US disclosed
US-20150289505-A1 HERBICIDE COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-15 US disclosed
US-9101140-B2 Cyclohexanone compounds and herbicides comprising the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-08-11 US disclosed
US-20140228219-A1 CYCLOHEXANONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-08-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140228219-A1 CYCLOHEXANONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME CBR3, CBR1, CYP2S1 CRBN 1417/4885ALDH1A1 1329/4885MAPT 4773/4885
US-20150289505-A1 HERBICIDE COMPOSITION DDT, DHFR, DERL1 CRBN 530/4885ALDH1A1 215/4885MAPT 1013/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.