SCHEMBL15944386

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15944368	0.90	ALDH1A1 (0.49)	ALDH1A1KDM4EHPGDCYP1A2CYP2C19
	SCHEMBL15944391	0.89	ALDH1A1 (0.48)	ALDH1A1HTTRAB9ASMN1; SMN2L3MBTL1
	SCHEMBL15945500	0.89	ALDH1A1 (0.48)	ALDH1A1KDM4EHTTRAB9ASMN1; SMN2
	SCHEMBL15944380	0.89	ALDH1A1 (0.50)	ALDH1A1KDM4EHTTHPGDCYP1A2
	SCHEMBL15945528	0.86	ALDH1A1 (0.45)	ALDH1A1KDM4ECYP1A2CYP2C19MAPT
	SCHEMBL15945536	0.86	ALDH1A1 (0.45)	ALDH1A1L3MBTL1POLBMAPK1
	SCHEMBL15945506	0.84	ALDH1A1 (0.44)	ALDH1A1KDM4EL3MBTL1MAPK1
	SCHEMBL15944418	0.80	ALDH1A1 (0.50)	ALDH1A1L3MBTL1POLBMAPK1
	SCHEMBL15944463	0.79	ALDH1A1 (0.42)	ALDH1A1KDM4ESMN1; SMN2MAPTL3MBTL1
	SCHEMBL15944453	0.77	ALDH1A1 (0.61)	ALDH1A1CYP1A2NPSR1SMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.