Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | CES2 | O00748 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL745694 | 0.80 | CES2 (0.56) | NPSR1CES2HTTMEN1KMT2A | |
| SCHEMBL30387424 | 0.80 | CES2 (0.56) | NPSR1CES2HTTMEN1KMT2A | |
| SCHEMBL745695 | 0.80 | CES2 (0.56) | NPSR1CES2HTTMEN1KMT2A | |
| SCHEMBL4039614 | 0.80 | CES2 (0.56) | NPSR1CES2HTTMEN1KMT2A | |
| SCHEMBL24119884 | 0.78 | NPSR1 (0.49) | NPSR1CES2HTTMEN1KMT2A | |
| SCHEMBL1085516 | 0.73 | KMT2A (0.40) | NPSR1CES2KMT2AGAAALDH1A1 | |
| SCHEMBL1085514 | 0.73 | KMT2A (0.40) | NPSR1CES2KMT2AGAAALDH1A1 | |
| Ethane SCHEMBL27364386 | 0.73 | CES2 (0.67) | NPSR1CES2HTTMEN1KMT2A | |
| SCHEMBL9137744 | 0.72 | NPC1 (0.53) | CES2MEN1KMT2A | |
| SCHEMBL15761220 | 0.72 | NPSR1 (0.53) | NPSR1CES2HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140228579-A1 | METHOD FOR THE CATALYTIC REDUCTION OF ACID CHLORIDES AND IMIDOYL CHLORIDES | Brock Unviersity (CA) | 2014-08-14 | — | — | US | disclosed |
| US-20140228579-A1 | METHOD FOR THE CATALYTIC REDUCTION OF ACID CHLORIDES AND IMIDOYL CHLORIDES | Brock Unviersity (CA) | 2014-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140228579-A1 | METHOD FOR THE CATALYTIC REDUCTION OF ACID CHLORIDES AND IMIDOYL CHLORIDES | CA6, RUVBL2, HACL2 | NPSR1 3995/4885CES2 220/4885HTT 4561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.