SCHEMBL1594623

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1595775	0.86	RAB9A (0.51)	NPC1RAB9AALDH1A1HSD17B2HSD17B1
	SCHEMBL1594605	0.85	RAB9A (0.57)	NPC1RAB9AALDH1A1HSD17B2HSD17B1
	SCHEMBL1593473	0.84	NPC1 (0.47)	NPC1RAB9AALDH1A1HSD17B2HSD17B1
	SCHEMBL1594289	0.83	RAB9A (0.73)	NPC1RAB9AALDH1A1MAPTHSD17B2
	SCHEMBL1593711	0.83	RAB9A (0.69)	NPC1RAB9AALDH1A1HSD17B2HSD17B1
	SCHEMBL1593772	0.82	NPC1 (0.47)	NPC1RAB9AALDH1A1HSD17B2HSD17B1
	SCHEMBL1594125	0.81	ALDH1A1 (0.54)	NPC1RAB9AALDH1A1HSD17B2HSD17B1
	SCHEMBL1594345	0.80	NPC1 (0.52)	NPC1RAB9AALDH1A1HSD17B2HSD17B1
	SCHEMBL1594718	0.78	ALDH1A1 (0.49)	NPC1RAB9AALDH1A1HSD17B2HSD17B1
	SCHEMBL1594109	0.78	NPC1 (0.50)	NPC1RAB9AALDH1A1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.