Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.32 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.32 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.32 |
| ▸ | PRKDC | P78527 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18861893 | 0.99 | PLA2G2A (0.32) | PLA2G2APLA2G4APLA2G10PRKDCHSP90AA1 | |
| SCHEMBL15946328 | 0.95 | PRKDC (0.31) | PLA2G2APLA2G4APLA2G10PRKDC | |
| SCHEMBL14822509 | 0.95 | KDM4E (0.34) | HSP90AA1HSP90AB1 | |
| SCHEMBL15946297 | 0.95 | KDM4E (0.34) | HSP90AA1HSP90AB1 | |
| SCHEMBL15946304 | 0.94 | PLA2G2A (0.32) | PLA2G2APLA2G4APRKDC | |
| SCHEMBL14822245 | 0.94 | HSP90AA1 (0.33) | HSP90AA1HSP90AB1 | |
| SCHEMBL14822638 | 0.93 | HSP90AA1 (0.34) | PLA2G2APLA2G4AHSP90AA1HSP90AB1 | |
| SCHEMBL22011972 | 0.92 | KDM4E (0.31) | — | |
| SCHEMBL20321655 | 0.92 | MAOA (0.32) | HSP90AA1HSP90AB1 | |
| SCHEMBL17885313 | 0.92 | HSP90AA1 (0.33) | PLA2G2APLA2G4AHSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9818948-B2 | Carbazole derivatives for organic electroluminescence devices | MERCK PATENT GMBH (DE) | 2017-11-14 | — | — | US | disclosed |
| US-9818948-B2 | Carbazole derivatives for organic electroluminescence devices | MERCK PATENT GMBH (DE) | 2017-11-14 | — | — | US | disclosed |
| US-20140225046-A1 | CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2014-08-14 | — | — | US | disclosed |
| US-20140225046-A1 | CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2014-08-14 | — | — | US | disclosed |