Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.32 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.32 |
| ▸ | PRKDC | P78527 | 2/20 | 0.31 |
| ▸ | TSPO | P30536 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15946328 | 0.98 | PRKDC (0.31) | PLA2G2APLA2G4APRKDCTSPOHDAC4 | |
| SCHEMBL14849838 | 0.96 | PRKDC (0.33) | PLA2G2APLA2G4APRKDCPGR | |
| SCHEMBL26510345 | 0.95 | PGR (0.31) | PRKDCPGR | |
| SCHEMBL18861893 | 0.94 | PLA2G2A (0.32) | PLA2G2APLA2G4APRKDCTSPO | |
| SCHEMBL21467964 | 0.94 | CASP3 (0.36) | PLA2G2APLA2G4APRKDCTSPOHDAC4 | |
| SCHEMBL14822245 | 0.94 | HSP90AA1 (0.33) | KDM4EPGR | |
| SCHEMBL16076424 | 0.94 | — | — | |
| SCHEMBL15946283 | 0.94 | PLA2G2A (0.32) | PLA2G2APLA2G4APRKDC | |
| SCHEMBL15946297 | 0.93 | KDM4E (0.34) | KDM4EATML3MBTL1PGR | |
| SCHEMBL14822509 | 0.93 | KDM4E (0.34) | KDM4EATML3MBTL1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9818948-B2 | Carbazole derivatives for organic electroluminescence devices | MERCK PATENT GMBH (DE) | 2017-11-14 | — | — | US | disclosed |
| US-9818948-B2 | Carbazole derivatives for organic electroluminescence devices | MERCK PATENT GMBH (DE) | 2017-11-14 | — | — | US | disclosed |
| EP-2758372-B1 | CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-05-17 | — | — | EP | disclosed |
| US-20140225046-A1 | CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2014-08-14 | — | — | US | disclosed |
| US-20140225046-A1 | CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2014-08-14 | — | — | US | disclosed |