Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16742142 | 0.85 | COXFA4 (0.53) | MAPTRAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL2811130 | 0.84 | CA12 (0.48) | MAPTRAB9ALMNATSHRCA12 | |
| SCHEMBL10407993 | 0.84 | MAPT (0.44) | MAPTRAB9ANPSR1NPC1RARB | |
| SCHEMBL20195015 | 0.84 | ALOX5 (0.45) | MAPTRAB9ASMN1; SMN2LMNAALOX5 | |
| SCHEMBL103150 | 0.83 | MAPT (0.47) | MAPTRAB9ANPC1KMT2AKDM4E | |
| SCHEMBL2812534 | 0.83 | RXRA (0.52) | MAPTALOX5CA12CA9CA1 | |
| SCHEMBL670503 | 0.81 | MAPT (0.61) | MAPTRAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL14898177 | 0.81 | CA12 (0.45) | MAPTRAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL17429685 | 0.81 | SMN1; SMN2 (0.43) | MAPTRAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL17385845 | 0.81 | MAPT (0.50) | MAPTRAB9ASMN1; SMN2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014121695-A1 | NOVEL XANTHINE OXIDASE INHIBITOR COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF | 镇江新元素医药科技有限公司 (CN) | 2014-08-14 | — | — | WO | disclosed |