Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 7/20 | 0.54 |
| ▸ | DBF4 | Q9UBU7 | 7/20 | 0.54 |
| ▸ | TRPM8 | Q7Z2W7 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL454793 | 0.86 | CDC7 (0.59) | CDC7DBF4TRPM8MAPTKDM4E | |
| SCHEMBL29627451 | 0.86 | CDC7 (0.59) | CDC7DBF4TRPM8MAPTKDM4E | |
| SCHEMBL12186978 | 0.81 | CDC7 (0.64) | CDC7DBF4TRPM8MAPTKDM4E | |
| SCHEMBL19523297 | 0.79 | CDC7 (0.62) | CDC7DBF4TRPM8MAPTKDM4E | |
| SCHEMBL455876 | 0.79 | CDC7 (0.62) | CDC7DBF4TRPM8MAPTKDM4E | |
| SCHEMBL8867093 | 0.79 | CDC7 (0.62) | CDC7DBF4TRPM8MAPTKDM4E | |
| SCHEMBL15383553 | 0.78 | ALDH1A1 (0.62) | CDC7DBF4TRPM8MAPTKDM4E | |
| SCHEMBL28381444 | 0.78 | CDC7 (0.57) | CDC7DBF4TRPM8MAPTKDM4E | |
| SCHEMBL31534636 | 0.78 | CDC7 (0.57) | CDC7DBF4TRPM8MAPTKDM4E | |
| SCHEMBL27838195 | 0.78 | CDC7 (0.57) | CDC7DBF4TRPM8MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014121695-A1 | NOVEL XANTHINE OXIDASE INHIBITOR COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF | 镇江新元素医药科技有限公司 (CN) | 2014-08-14 | — | — | WO | disclosed |