Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 8/20 | 0.62 |
| ▸ | DBF4 | Q9UBU7 | 8/20 | 0.62 |
| ▸ | TRPM8 | Q7Z2W7 | 6/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | DHODH | Q02127 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12186978 | 0.88 | CDC7 (0.64) | CDC7DBF4TRPM8MAPTKDM4E | |
| SCHEMBL8867336 | 0.86 | CDC7 (0.62) | CDC7DBF4TRPM8MAPTKDM4E | |
| SCHEMBL19523297 | 0.85 | CDC7 (0.62) | CDC7DBF4TRPM8MAPTKDM4E | |
| SCHEMBL455876 | 0.85 | CDC7 (0.62) | CDC7DBF4TRPM8MAPTKDM4E | |
| SCHEMBL15383553 | 0.84 | ALDH1A1 (0.62) | CDC7DBF4TRPM8MAPTKDM4E | |
| SCHEMBL29627451 | 0.83 | CDC7 (0.59) | CDC7DBF4TRPM8MAPTKDM4E | |
| SCHEMBL454793 | 0.83 | CDC7 (0.59) | CDC7DBF4TRPM8MAPTKDM4E | |
| SCHEMBL2885708 | 0.83 | TRPM8 (0.78) | CDC7DBF4TRPM8MAPTKDM4E | |
| SCHEMBL19523327 | 0.82 | MAPT (0.58) | CDC7DBF4TRPM8MAPTKDM4E | |
| SCHEMBL30804867 | 0.82 | CDC7 (0.58) | CDC7DBF4TRPM8MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2927219-B1 | 2-ARYL SELENAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF | ATOM BIOSCIENCE AND PHARMACEUTICAL CO LTD (CN) | 2018-05-30 | — | — | EP | disclosed |
| US-9802907-B2 | 2-aryl selenazole compound and pharmaceutical composition thereof | JIANGSU ATOM BIOSCIENCE AND PHARMACEUTICAL CO., LTD. (CN) | 2017-10-31 | — | — | US | disclosed |
| US-5614520-A | 2-arylthiazole derivatives and pharmaceutical composition thereof | TEIJIN LIMITED (JP) | 1997-03-25 | — | — | US | disclosed |
| EP-0513379-B1 | 2-ARYLTHIAZOLE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | TEIJIN LTD (JP) | 1996-09-11 | — | — | EP | disclosed |
| EP-0513379-A1 | 2-ARYLTHIAZOLE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | TEIJIN LIMITED (JP) | 1992-11-19 | — | — | EP | disclosed |