Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 9/20 | 0.59 |
| ▸ | DBF4 | Q9UBU7 | 9/20 | 0.59 |
| ▸ | TRPM8 | Q7Z2W7 | 7/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL454793 | 1.00 | CDC7 (0.59) | CDC7DBF4TRPM8MAPTKDM4E | |
| SCHEMBL15947327 | 0.86 | CDC7 (0.54) | CDC7DBF4TRPM8MAPTKDM4E | |
| SCHEMBL12186978 | 0.85 | CDC7 (0.64) | CDC7DBF4TRPM8MAPTKDM4E | |
| SCHEMBL31534636 | 0.84 | CDC7 (0.57) | CDC7DBF4TRPM8MAPTKDM4E | |
| SCHEMBL27838195 | 0.84 | CDC7 (0.57) | CDC7DBF4TRPM8MAPTKDM4E | |
| SCHEMBL28381444 | 0.84 | CDC7 (0.57) | CDC7DBF4TRPM8MAPTKDM4E | |
| SCHEMBL2009745 | 0.84 | RAB9A (0.59) | KDM4EALDH1A1KMT2A | |
| SCHEMBL19523297 | 0.83 | CDC7 (0.62) | CDC7DBF4TRPM8MAPTKDM4E | |
| SCHEMBL455876 | 0.83 | CDC7 (0.62) | CDC7DBF4TRPM8MAPTKDM4E | |
| SCHEMBL8867093 | 0.83 | CDC7 (0.62) | CDC7DBF4TRPM8MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119504640-A | Febuxostat preparation technology | 哈药集团技术中心 | 2025-02-25 | — | — | CN | claimed |
| CN-117924211-A | Preparation method of febuxostat | 哈药集团技术中心 | 2024-04-26 | — | — | CN | claimed |
| CN-117069675-A | Preparation method of febuxostat | 河北冀衡药业股份有限公司 | 2023-11-17 | — | — | CN | claimed |
| CN-110790720-B | Novel preparation method of febuxostat intermediate | 内蒙古京东药业有限公司 | 2023-06-27 | — | — | CN | claimed |
| CN-111039891-B | Method for synthesizing febuxostat and intermediate thereof | 杭州朱养心药业有限公司 | 2025-03-28 | — | — | CN | disclosed |
| CN-111072591-B | Febuxostat and intermediates and synthesis thereof | 杭州朱养心药业有限公司 | 2025-03-28 | — | — | CN | disclosed |
| CN-119504640-A | Febuxostat preparation technology | 哈药集团技术中心 | 2025-02-25 | — | — | CN | disclosed |
| CN-110824067-B | Method for detecting genotoxic impurities in febuxostat | 天津药物研究院有限公司 | 2024-12-27 | — | — | CN | disclosed |
| CN-115772137-B | Preparation method of febuxostat | 济宁晟泰药业有限公司 | 2024-05-10 | — | — | CN | disclosed |
| CN-117924211-A | Preparation method of febuxostat | 哈药集团技术中心 | 2024-04-26 | — | — | CN | disclosed |
| CN-114560837-B | Chromone compound and preparation method and application thereof | 五邑大学 | 2023-11-24 | — | — | CN | disclosed |
| CN-117069675-A | Preparation method of febuxostat | 河北冀衡药业股份有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-110229117-B | Novel preparation method of febuxostat | 福安药业集团重庆博圣制药有限公司 | 2023-04-18 | — | — | CN | disclosed |
| CN-109912531-B | Preparation method of high-purity febuxostat | 湖南方盛制药股份有限公司 | 2023-03-10 | — | — | CN | disclosed |
| CN-115772137-A | Preparation method of febuxostat | 济宁晟泰药业有限公司 | 2023-03-10 | — | — | CN | disclosed |
| CN-114560837-A | Chromone compound and preparation method and application thereof | 五邑大学 | 2022-05-31 | — | — | CN | disclosed |