Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17368178 | 0.88 | SMN1; SMN2 (0.59) | SMN1; SMN2NPC1RAB9ATP53HTT | |
| SCHEMBL14903117 | 0.84 | SMN1; SMN2 (0.57) | SMN1; SMN2NPC1RAB9ATP53HTT | |
| SCHEMBL5837409 | 0.83 | SMN1; SMN2 (0.58) | SMN1; SMN2NPC1RAB9ATP53HTT | |
| SCHEMBL7924409 | 0.81 | RAB9A (0.56) | SMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL28413462 | 0.79 | ALDH1A1 (0.61) | SMN1; SMN2NPC1RAB9ATP53GAA | |
| SCHEMBL28405067 | 0.79 | NPC1 (0.57) | SMN1; SMN2NPC1RAB9ATP53HTT | |
| SCHEMBL6361249 | 0.79 | SMN1; SMN2 (0.61) | SMN1; SMN2NPC1RAB9ATP53HTT | |
| SCHEMBL10253052 | 0.79 | SMN1; SMN2 (0.65) | SMN1; SMN2RAB9A | |
| SCHEMBL3794688 | 0.78 | RAB9A (0.62) | SMN1; SMN2NPC1RAB9ATP53HTT | |
| SCHEMBL24101621 | 0.78 | HTT (0.61) | SMN1; SMN2NPC1RAB9ATP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014122066-A1 | SUBSTITUTED AMINO AZOLES AS PLANT GROWTH REGULATORS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-08-14 | — | — | WO | disclosed |