Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6399291 | 0.78 | CYP2D6 (0.54) | KMT2AMEN1TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1872795 | 0.78 | MTNR1A (0.43) | KMT2AMEN1TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8179424 | 0.77 | ALDH1A1 (0.43) | KMT2AMEN1TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3784058 | 0.76 | KMT2A (0.41) | KMT2AMEN1TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL30366355 | 0.76 | MEN1 (0.41) | KMT2AMEN1TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL12969433 | 0.74 | MEN1 (0.44) | KMT2AMEN1TDP1SMN1; SMN2MAPK1 | |
| SCHEMBL11006707 | 0.74 | KMT2A (0.40) | KMT2AMEN1TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5666441 | 0.74 | SMN1; SMN2 (0.42) | KMT2AMEN1TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL18469615 | 0.73 | KMT2A (0.39) | KMT2AMEN1TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13499248 | 0.73 | MEN1 (0.39) | KMT2AMEN1TDP1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2953948-B1 | FLUORINATED INTEGRIN ANTAGONISTS | SCIFLUOR LIFE SCIENCES INC (US) | 2017-09-27 | — | — | EP | disclosed |
| WO-2014124302-A1 | FLUORINATED INTEGRIN ANTAGONISTS | SCIFLUOR LIFE SCIENCES, LLC (US) | 2014-08-14 | — | — | WO | disclosed |