Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3891366 | 1.00 | ALDH1A1 (0.45) | ALDH1A1TDP1KDM4ESLC18A2SMN1; SMN2 | |
| SCHEMBL11527033 | 1.00 | ALDH1A1 (0.45) | ALDH1A1TDP1KDM4ESLC18A2SMN1; SMN2 | |
| SCHEMBL3900802 | 0.93 | KDM4E (0.42) | ALDH1A1TDP1KDM4ESLC18A2SMN1; SMN2 | |
| SCHEMBL19689466 | 0.92 | KDM4E (0.39) | ALDH1A1TDP1KDM4EMEN1HTT | |
| SCHEMBL19689444 | 0.92 | KDM4E (0.39) | ALDH1A1TDP1KDM4EMEN1HTT | |
| SCHEMBL19708381 | 0.92 | KDM4E (0.39) | ALDH1A1TDP1KDM4EMEN1HTT | |
| SCHEMBL415516 | 0.90 | KDM4E (0.40) | ALDH1A1TDP1KDM4EMEN1HTT | |
| SCHEMBL8402102 | 0.86 | KDM4E (0.45) | ALDH1A1KDM4EMEN1HTTKMT2A | |
| SCHEMBL415515 | 0.86 | KDM4E (0.40) | ALDH1A1TDP1KDM4EMEN1HTT | |
| SCHEMBL13888541 | 0.84 | KDM4E (0.34) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140227212-A1 | POLYMERIZED SUNSCREEN ABSORBERS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2014-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140227212-A1 | POLYMERIZED SUNSCREEN ABSORBERS | PCNA, MCM3, SYMPK | ALDH1A1 2364/4885TDP1 2017/4885KDM4E 4199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.