Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.30 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15875878 | 0.92 | CHRNB2 (0.37) | CHRNB2CHRNA4 | |
| SCHEMBL15948198 | 0.86 | PDE7B (0.32) | PDE7B | |
| SCHEMBL15925813 | 0.79 | IP6K1 (0.39) | CHRNB2CHRNA4 | |
| SCHEMBL15925815 | 0.77 | CHRNB2 (0.37) | CHRNB2CHRNA4 | |
| SCHEMBL13386268 | 0.77 | KMT2A (0.34) | — | |
| SCHEMBL15948227 | 0.76 | SNCA (0.35) | — | |
| SCHEMBL15875883 | 0.73 | CHRNB2 (0.48) | CYP3A4CYP2D6CHRNB2CHRNA4 | |
| SCHEMBL15875850 | 0.73 | — | — | |
| SCHEMBL15948214 | 0.72 | CRHR1 (0.32) | — | |
| SCHEMBL15948217 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8809317-B2 | Antiviral compounds | PROSETTA ANTIVIRAL INC. (US) | 2014-08-19 | — | — | US | claimed |