Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15948198 | 0.88 | PDE7B (0.32) | — | |
| SCHEMBL12812986 | 0.86 | SNCA (0.47) | SNCANOX1MEN1LMNAGAA | |
| SCHEMBL15948223 | 0.83 | CRHR1 (0.35) | SNCANOX1MEN1LMNAGAA | |
| SCHEMBL15948812 | 0.81 | SNCA (0.35) | SNCANOX1MEN1LMNAGAA | |
| SCHEMBL15948197 | 0.80 | CRHR1 (0.40) | SNCAMAPTCASP3 | |
| SCHEMBL5725873 | 0.79 | SNCA (0.41) | SNCANOX1MEN1LMNAGAA | |
| SCHEMBL12813044 | 0.77 | SNCA (0.32) | SNCAIDH1 | |
| SCHEMBL28078652 | 0.76 | MAPT (0.39) | SNCANOX1MEN1LMNAGAA | |
| SCHEMBL15948157 | 0.76 | SLC29A1 (0.34) | — | |
| SCHEMBL15875878 | 0.74 | CHRNB2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8809317-B2 | Antiviral compounds | PROSETTA ANTIVIRAL INC. (US) | 2014-08-19 | — | — | US | claimed |