SCHEMBL15948722

SCHEMBL15948722

CCCCCCCCCCCCCCCC[C@H](CO)NC(=O)C(F)(F)F

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.50
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
FAAH O00519 7/20 0.42
CES1 P23141 5/20 0.42
CES2 O00748 3/20 0.42
CYP1A2 P05177 1/20 0.42
HSD17B10 Q99714 1/20 0.42
LMNA P02545 1/20 0.41
ASAH1 Q13510 1/20 0.41
MAPT P10636 1/20 0.41
MLYCD O95822 1/20 0.40
PLA2G2C Q5R387 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15942203 1.00 EPHX1 (0.50) EPHX1MEN1KMT2AFAAHCES1
SCHEMBL18349792 0.98 EPHX1 (0.47) EPHX1MEN1KMT2AFAAHCES1
SCHEMBL24371436 0.93 EPHX1 (0.44) EPHX1MEN1KMT2AFAAHCES1
SCHEMBL17972439 0.88 EPHX1 (0.51) EPHX1MEN1KMT2AFAAHCES1
SCHEMBL19352538 0.86 EPHX1 (0.39) EPHX1MEN1KMT2AMLYCD
SCHEMBL20830172 0.86 EPHX1 (0.39) EPHX1MEN1KMT2AMLYCD
SCHEMBL16393079 0.84 ALDH1A1 (0.36) EPHX1MEN1KMT2A
SCHEMBL16575957 0.81 EPHX1 (0.45) EPHX1MEN1KMT2AFAAHCES1
SCHEMBL5267236 0.80 EPHX1 (0.44) EPHX1MEN1KMT2AFAAHCES1
SCHEMBL5269901 0.80 EPHX1 (0.44) EPHX1MEN1KMT2AFAAHCES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4094767-B1 NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO UNIV EMORY (US) 2026-05-20 EP disclosed
EP-3448392-B1 ALKYNE CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO UNIV EMORY (US) 2026-05-13 EP disclosed
US-20260124226-A1 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO UNIV EMORY (US) 2026-05-07 US disclosed
US-20260102422-A1 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO UNIV EMORY (US) 2026-04-16 US disclosed
US-20260053838-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING SUBSTITUTED NUCLEOTIDES AND NUCLEOSIDES FOR TREATING VIRAL INFECTIONS UNIV EMORY (US) 2026-02-26 US disclosed
US-12414961-B2 Substituted nucleosides and nucleotides for treating viral infections EMORY UNIVERSITY (US) 2025-09-16 US disclosed
US-20250281519-A1 NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS, COMBINATIONS AND USES RELATED THERETO EMORY UNIVERSITY 2025-09-11 US disclosed
US-20240180948-A1 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO EMORY UNIVERSITY 2024-06-06 US disclosed
US-20240173345-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING SUBSTITUTED NUCLEOTIDE AND NUCLEOSIDE FOR TREATING VIRAL INFECTIONS EMORY UNIVERSITY 2024-05-30 US disclosed
US-20240165143-A1 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO EMORY UNIVERSITY 2024-05-23 US disclosed
WO-2017189978-A1 ALKYNE CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO EMORY UNIVERSITY (US) 2017-11-02 WO disclosed
WO-2017155923-A1 NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO EMORY UNIVERSITY (US) 2017-09-14 WO disclosed
WO-2017106710-A1 NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO EMORY UNIVERSITY (US) 2017-06-22 WO disclosed
WO-2016145142-A1 NUCLEOTIDE AND NUCLEOSIDE THERAPEUTICS COMPOSITIONS AND USES RELATED THERETO EMORY UNIVERSITY (US) 2016-09-15 WO disclosed
WO-2016145142-A1 NUCLEOTIDE AND NUCLEOSIDE THERAPEUTICS COMPOSITIONS AND USES RELATED THERETO EMORY UNIVERSITY (US) 2016-09-15 WO disclosed
US-20160220595-A1 NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO DEFENSE THREAT REDUCTION AGENCY, US DOD 2016-08-04 US disclosed
US-20160220595-A1 NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO DEFENSE THREAT REDUCTION AGENCY, US DOD 2016-08-04 US disclosed
US-20160220595-A1 NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO DEFENSE THREAT REDUCTION AGENCY, US DOD 2016-08-04 US disclosed
WO-2015038596-A1 NUCLEOTIDE AND NUCLEOSIDE COMPOSITIONS AND USES RELATED THERETO EMORY UNIVERSITY (US) 2015-03-19 WO disclosed
WO-2014124430-A1 NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO EMORY UNIVERSITY (US) 2014-08-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160220595-A1 NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO PNP, NTPCR, TYMP EPHX1 1225/4885MEN1 3476/4885KMT2A 3432/4885
US-20260102422-A1 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO SARS1, ITK, SLC43A1 EPHX1 1573/4885MEN1 4748/4885KMT2A 2592/4885
US-20260053838-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING SUBSTITUTED NUCLEOTIDES AND NUCLEOSIDES FOR TREATING VIRAL INFECTIONS DCTD, RNMT, NSUN2 EPHX1 1659/4885MEN1 3012/4885KMT2A 2818/4885
US-20260124226-A1 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO NSUN2, SARS1, SNRPE EPHX1 464/4885MEN1 4825/4885KMT2A 2511/4885
US-20250281519-A1 NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS, COMBINATIONS AND USES RELATED THERETO NTPCR, TYMP, MTAP EPHX1 896/4885MEN1 2627/4885KMT2A 3425/4885
US-20240173345-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING SUBSTITUTED NUCLEOTIDE AND NUCLEOSIDE FOR TREATING VIRAL INFECTIONS PNP, NTPCR, TYMP EPHX1 2328/4885MEN1 3240/4885KMT2A 3396/4885
US-20240180948-A1 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO PNP, PRPF4, HPRT1 EPHX1 685/4885MEN1 4756/4885KMT2A 2346/4885
US-12414961-B2 Substituted nucleosides and nucleotides for treating viral infections PNP, NTPCR, TYMP EPHX1 1725/4885MEN1 2982/4885KMT2A 2603/4885
US-20240165143-A1 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO PNP, PRPF4, HPRT1 EPHX1 685/4885MEN1 4756/4885KMT2A 2346/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.