SCHEMBL1594980

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15905607	0.87	CYP2C9 (0.49)	NQO2LMNANPC1RAB9AALDH1A1
	SCHEMBL12706090	0.86	NQO2 (0.45)	NQO2NPC1RAB9AALDH1A1PHGDH
	SCHEMBL1593629	0.83	NPC1 (0.52)	NPC1RAB9AALDH1A1RARGRXRA
	SCHEMBL1594352	0.82	RAB9A (0.64)	LMNANPC1RAB9AALDH1A1KDM4E
	SCHEMBL1596407	0.78	RAB9A (0.62)	NPC1RAB9AALDH1A1PHGDHSMN1; SMN2
	SCHEMBL3447083	0.77	CYP2C9 (0.55)	NQO2LMNANPC1RAB9AALDH1A1
	SCHEMBL1593870	0.77	ALDH1A1 (0.53)	NPC1RAB9AALDH1A1RXRASMN1; SMN2
	SCHEMBL1594109	0.76	NPC1 (0.50)	NPC1RAB9AALDH1A1MAPTSMN1; SMN2
	SCHEMBL1593772	0.75	NPC1 (0.47)	NPC1RAB9AALDH1A1SMN1; SMN2
	SCHEMBL1593680	0.74	RAB9A (0.70)	NPC1RAB9AALDH1A1RXRAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.