SCHEMBL15955490

SCHEMBL15955490

Cc1cc(C)cc(Sc2cc(Cl)c(NN)c(Cl)c2)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 4/20 0.39
HTT P42858 1/20 0.34
TUBB4A P04350 1/20 0.34
TUBB P07437 1/20 0.34
TUBA3C P0DPH7 1/20 0.34
IDO1 P14902 1/20 0.34
TUBA1B P68363 1/20 0.34
TUBA4A P68366 1/20 0.34
TUBB4B P68371 1/20 0.34
TUBB3 Q13509 1/20 0.34
TUBB2A Q13885 1/20 0.34
TUBB8 Q3ZCM7 1/20 0.34
TUBA3E Q6PEY2 1/20 0.34
TUBA1A Q71U36 1/20 0.34
TUBA1C Q9BQE3 1/20 0.34
TUBB6 Q9BUF5 1/20 0.34
TUBB2B Q9BVA1 1/20 0.34
TUBB1 Q9H4B7 1/20 0.34
TSHR P16473 2/20 0.31
ALDH1A1 P00352 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15955533 0.85 ALDH1A1 (0.37) RAPGEF4ALDH1A1MAPT
SCHEMBL10700106 0.81 RAPGEF4 (0.43) RAPGEF4HTTTSHRALDH1A1MAPT
SCHEMBL15955672 0.78 ALDH1A1 (0.48) RAPGEF4TUBB4ATUBBTUBA3CIDO1
SCHEMBL15955601 0.77 CHRNA7 (0.39) IDO1ALDH1A1
SCHEMBL15955703 0.76 PKM (0.44) RAPGEF4
SCHEMBL15955710 0.74 PTGIR (0.45) IDO1MAPT
SCHEMBL3689119 0.73 ALDH1A1 (0.44) RAPGEF4TUBB4ATUBBTUBA3CIDO1
SCHEMBL15955545 0.73 ALDH1A1 (0.47) RAPGEF4HTTTSHRALDH1A1MAPT
SCHEMBL15955641 0.72 ALDH1A1 (0.40) ALDH1A1MAPT
SCHEMBL11774357 0.71 RAPGEF4 (0.53) RAPGEF4HTTTSHRALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014126580-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2014-08-21 WO disclosed