Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MLYCD | O95822 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8570516 | 0.94 | GAA (0.41) | GAAMLYCDMEN1KMT2ACHRM2 | |
| SCHEMBL28659354 | 0.74 | ALDH1A1 (0.41) | GAAMEN1KMT2ACHRM2POLB | |
| SCHEMBL8570960 | 0.73 | CHRM2 (0.45) | GAAMEN1KMT2ACHRM2POLB | |
| SCHEMBL8569587 | 0.71 | GAA (0.41) | GAAMEN1KMT2ACHRM2POLB | |
| SCHEMBL275345 | 0.71 | ALDH1A1 (0.44) | GAAMEN1KMT2ACHRM2POLB | |
| Furfuryl Alcohol SCHEMBL5035658 | 0.71 | ALDH1A1 (0.42) | GAAMLYCDMEN1KMT2ACHRM2 | |
| SCHEMBL28009434 | 0.69 | ALOX5 (0.49) | GAAMLYCDPOLBHPGDMAPT | |
| SCHEMBL17064864 | 0.69 | ALDH1A1 (0.49) | GAAMLYCDMEN1KMT2ACHRM2 | |
| SCHEMBL12812535 | 0.68 | ALDH1A1 (0.46) | GAAMEN1KMT2ACHRM2POLB | |
| SCHEMBL8323969 | 0.68 | SLC6A2 (0.45) | GAAMEN1KMT2ACHRM2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9856275-B2 | Synthesis and use of fluorinated compounds | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2018-01-02 | — | — | US | disclosed |
| US-20160002270-A1 | SYNTHESIS AND USE OF FLUORINATED COMPOUNDS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-01-07 | — | — | US | disclosed |
| WO-2014126990-A1 | SYNTHESIS AND USE OF FLUORINATED COMPOUNDS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2014-08-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160002270-A1 | SYNTHESIS AND USE OF FLUORINATED COMPOUNDS | AFF2, AFF4, AFF1 | GAA 3381/4885MLYCD 1869/4885MEN1 1550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.