Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CECR2 | Q9BXF3 | 2/20 | 0.57 |
| ▸ | BRD4 | O60885 | 15/20 | 0.52 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.51 |
| ▸ | TAF1 | P21675 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15956839 | 0.91 | CECR2 (0.55) | CECR2BRD4BRD9TAF1PARP1 | |
| SCHEMBL15957213 | 0.90 | CECR2 (0.56) | CECR2BRD4BRD9TAF1 | |
| SCHEMBL15964609 | 0.89 | BRD9 (0.59) | CECR2BRD4BRD9TAF1HDAC1 | |
| SCHEMBL15957196 | 0.89 | CECR2 (0.55) | CECR2BRD4BRD9TAF1 | |
| SCHEMBL15957091 | 0.89 | CECR2 (0.55) | CECR2BRD4BRD9TAF1 | |
| SCHEMBL15957032 | 0.88 | CECR2 (0.54) | CECR2BRD4BRD9TAF1 | |
| SCHEMBL15956889 | 0.87 | CECR2 (0.51) | CECR2BRD4BRD9TAF1HDAC1 | |
| SCHEMBL15956937 | 0.87 | CECR2 (0.53) | CECR2BRD4BRD9TAF1 | |
| SCHEMBL15957174 | 0.87 | CECR2 (0.53) | CECR2BRD4BRD9TAF1 | |
| SCHEMBL15956878 | 0.86 | CECR2 (0.52) | CECR2BRD4BRD9TAF1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014125408-A2 | SUBSTITUTED 1H-PYRROLOPYRIDINONE DERIVATIVES AS KINASE INHIBITORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2014-08-21 | — | — | WO | claimed |
| WO-2014125408-A2 | SUBSTITUTED 1H-PYRROLOPYRIDINONE DERIVATIVES AS KINASE INHIBITORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2014-08-21 | — | — | WO | disclosed |
| WO-2014125408-A2 | SUBSTITUTED 1H-PYRROLOPYRIDINONE DERIVATIVES AS KINASE INHIBITORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2014-08-21 | — | — | WO | disclosed |