Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CECR2 | Q9BXF3 | 3/20 | 0.56 |
| ▸ | BRD4 | O60885 | 9/20 | 0.51 |
| ▸ | BTK | Q06187 | 4/20 | 0.51 |
| ▸ | DHPS | P49366 | 1/20 | 0.51 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.50 |
| ▸ | TAF1 | P21675 | 1/20 | 0.48 |
| ▸ | CLK2 | P49760 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15964609 | 0.94 | BRD9 (0.59) | CECR2BRD4BTKBRD9TAF1 | |
| SCHEMBL15964519 | 0.92 | CECR2 (0.53) | CECR2BRD4BTKDHPSBRD9 | |
| SCHEMBL15956839 | 0.92 | CECR2 (0.55) | CECR2BRD4BRD9TAF1 | |
| SCHEMBL15956937 | 0.91 | CECR2 (0.53) | CECR2BRD4BTKDHPSBRD9 | |
| SCHEMBL15956896 | 0.91 | BTK (0.50) | CECR2BRD4BTKDHPSBRD9 | |
| SCHEMBL15957020 | 0.90 | BTK (0.46) | CECR2BRD4BTKDHPSBRD9 | |
| SCHEMBL15957166 | 0.90 | CECR2 (0.57) | CECR2BRD4BRD9TAF1 | |
| SCHEMBL15956785 | 0.89 | BRD9 (0.52) | CECR2BRD4BTKDHPSBRD9 | |
| SCHEMBL15957196 | 0.88 | CECR2 (0.55) | CECR2BRD4BRD9TAF1 | |
| SCHEMBL15957091 | 0.88 | CECR2 (0.55) | CECR2BRD4BRD9TAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014125408-A2 | SUBSTITUTED 1H-PYRROLOPYRIDINONE DERIVATIVES AS KINASE INHIBITORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2014-08-21 | — | — | WO | disclosed |