Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD9 | Q9H8M2 | 6/20 | 0.59 |
| ▸ | CECR2 | Q9BXF3 | 4/20 | 0.55 |
| ▸ | BRD4 | O60885 | 10/20 | 0.51 |
| ▸ | TAF1 | P21675 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | BTK | Q06187 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15957213 | 0.94 | CECR2 (0.56) | BRD9CECR2BRD4TAF1BTK | |
| SCHEMBL15956839 | 0.91 | CECR2 (0.55) | BRD9CECR2BRD4TAF1HDAC1 | |
| SCHEMBL15956937 | 0.91 | CECR2 (0.53) | BRD9CECR2BRD4TAF1BTK | |
| SCHEMBL15957166 | 0.89 | CECR2 (0.57) | BRD9CECR2BRD4TAF1HDAC1 | |
| SCHEMBL15957091 | 0.88 | CECR2 (0.55) | BRD9CECR2BRD4TAF1 | |
| SCHEMBL15957196 | 0.88 | CECR2 (0.55) | BRD9CECR2BRD4TAF1 | |
| SCHEMBL15957032 | 0.86 | CECR2 (0.54) | BRD9CECR2BRD4TAF1BTK | |
| SCHEMBL15964519 | 0.86 | CECR2 (0.53) | BRD9CECR2BRD4TAF1BTK | |
| SCHEMBL15956889 | 0.85 | CECR2 (0.51) | BRD9CECR2BRD4TAF1HDAC1 | |
| SCHEMBL15957174 | 0.85 | CECR2 (0.53) | BRD9CECR2BRD4TAF1BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014125408-A2 | SUBSTITUTED 1H-PYRROLOPYRIDINONE DERIVATIVES AS KINASE INHIBITORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2014-08-21 | — | — | WO | disclosed |