Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PEPD | P12955 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GNAI3 | P08754 | 4/20 | 0.34 |
| ▸ | GNAO1 | P09471 | 4/20 | 0.34 |
| ▸ | GNAI1 | P63096 | 4/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14451902 | 0.81 | ALDH1A1 (0.40) | NCF1SMN1; SMN2ALDH1A1HTTLMNA | |
| SCHEMBL8351923 | 0.80 | HTT (0.41) | NCF1SMN1; SMN2ALDH1A1HTTLMNA | |
| SCHEMBL15508724 | 0.80 | NCF1 (0.38) | NCF1SMN1; SMN2ALDH1A1HTTLMNA | |
| SCHEMBL24694438 | 0.79 | EPHX2 (0.41) | SMN1; SMN2GAACYP1A2TDP1 | |
| SCHEMBL13714198 | 0.78 | ALDH1A1 (0.39) | NCF1SMN1; SMN2ALDH1A1HTTLMNA | |
| SCHEMBL942233 | 0.78 | NLRP3 (0.41) | NCF1SMN1; SMN2ALDH1A1HTTLMNA | |
| SCHEMBL13783634 | 0.78 | ALDH1A1 (0.37) | NCF1SMN1; SMN2ALDH1A1HTTLMNA | |
| SCHEMBL3981214 | 0.78 | ALDH1A1 (0.37) | NCF1SMN1; SMN2ALDH1A1HTTLMNA | |
| SCHEMBL2468570 | 0.78 | — | — | |
| SCHEMBL15957773 | 0.78 | HRH3 (0.41) | SMN1; SMN2ALDH1A1PEPDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8809330-B2 | Pyrazolo[1,5-A]pyrimidines for antiviral treatment | GILEAD SCIENCES, INC. (US) | 2014-08-19 | — | — | US | disclosed |