SCHEMBL15958629

SCHEMBL15958629

COc1nc2ccccc2nc1C(=O)Nc1ccccc1

nearest known ligand 0.82

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.54
ADORA3 P0DMS8 3/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13595025 0.84 KDM4E (0.53)
SCHEMBL12669883 0.84 ADORA3 (0.48) ADORA3
SCHEMBL5717618 0.82 ALDH1A1 (0.67) MAPT
SCHEMBL31137919 0.82 ALDH1A1 (0.67) MAPT
SCHEMBL17089209 0.80 SCN10A (0.77)
SCHEMBL27828414 0.80 MAPT (0.66) MAPTADORA3
SCHEMBL15958659 0.79 MAPK1 (0.46) MAPT
SCHEMBL15945345 0.78 MAPT (0.55) MAPT
SCHEMBL9703688 0.78 NPC1 (0.45) MAPT
SCHEMBL6659522 0.78 ADORA3 (0.56) MAPTADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8809264-B2 Quinoxalinyl macrocyclic hepatitis C virus serine protease inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2014-08-19 US disclosed