Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | SMO | Q99835 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15958629 | 0.78 | MAPT (0.54) | MAPT | |
| SCHEMBL9703856 | 0.76 | GRIN2D (0.49) | MEN1KMT2APOLBLMNASMN1; SMN2 | |
| SCHEMBL9704050 | 0.75 | GRIN2D (0.62) | NPC1RAB9AMEN1KMT2ALMNA | |
| SCHEMBL9703955 | 0.70 | HRH4 (0.43) | RAB9APOLBLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL15945345 | 0.67 | MAPT (0.55) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL31137919 | 0.67 | ALDH1A1 (0.67) | MEN1KMT2APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL5717618 | 0.67 | ALDH1A1 (0.67) | MEN1KMT2APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL22093214 | 0.66 | KDM4E (0.52) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL7605864 | 0.66 | KMT2A (0.61) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL11342623 | 0.66 | SMN1; SMN2 (0.59) | NPC1RAB9AMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992011245-A1 | 2-ACYLAMIDO DERIVATIVES OF 3,4-DIHYDRO-3-OXO-QUINOXALINE HAVING PHARMACEUTICAL ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1992-07-09 | — | — | WO | disclosed |