Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 8/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12116414 | 1.00 | CCR2 (0.43) | CCR2MAPTHTTALDH1A1KDM4E | |
| SCHEMBL12116735 | 1.00 | CCR2 (0.43) | CCR2MAPTHTTALDH1A1KDM4E | |
| SCHEMBL7618478 | 1.00 | CCR2 (0.43) | CCR2MAPTHTTALDH1A1KDM4E | |
| SCHEMBL15958834 | 1.00 | CCR2 (0.43) | CCR2MAPTHTTALDH1A1KDM4E | |
| SCHEMBL30152453 | 0.98 | CCR2 (0.42) | CCR2MAPTHTTALDH1A1KDM4E | |
| SCHEMBL13158339 | 0.98 | CCR2 (0.41) | CCR2MAPTHTTALDH1A1KDM4E | |
| SCHEMBL17138494 | 0.96 | CCR2 (0.40) | CCR2MAPTHTTALDH1A1KDM4E | |
| SCHEMBL13158345 | 0.93 | L3MBTL1 (0.40) | CCR2MAPTHTTALDH1A1KDM4E | |
| SCHEMBL17138565 | 0.93 | L3MBTL1 (0.40) | CCR2MAPTHTTALDH1A1KDM4E | |
| SCHEMBL9410053 | 0.89 | MAPT (0.36) | CCR2MAPTHTTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8809538-B2 | Piperidine-containing compounds and use thereof | ARRAY BIOPHARMA INC. (US) | 2014-08-19 | — | — | US | disclosed |