Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 8/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12116414 | 1.00 | CCR2 (0.43) | CCR2MAPTHTTALDH1A1KDM4E | |
| SCHEMBL12116735 | 1.00 | CCR2 (0.43) | CCR2MAPTHTTALDH1A1KDM4E | |
| SCHEMBL15958833 | 1.00 | CCR2 (0.43) | CCR2MAPTHTTALDH1A1KDM4E | |
| SCHEMBL15958834 | 1.00 | CCR2 (0.43) | CCR2MAPTHTTALDH1A1KDM4E | |
| SCHEMBL30152453 | 0.98 | CCR2 (0.42) | CCR2MAPTHTTALDH1A1KDM4E | |
| SCHEMBL13158339 | 0.98 | CCR2 (0.41) | CCR2MAPTHTTALDH1A1KDM4E | |
| SCHEMBL17138494 | 0.96 | CCR2 (0.40) | CCR2MAPTHTTALDH1A1KDM4E | |
| SCHEMBL13158345 | 0.93 | L3MBTL1 (0.40) | CCR2MAPTHTTALDH1A1KDM4E | |
| SCHEMBL17138565 | 0.93 | L3MBTL1 (0.40) | CCR2MAPTHTTALDH1A1KDM4E | |
| SCHEMBL9410053 | 0.89 | MAPT (0.36) | CCR2MAPTHTTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106268348-B | A kind of preparation method of super-hydrophobic polyphenylene sulfide film | 天津津纶新材料科技有限公司 | 2019-10-22 | — | — | CN | claimed |
| CN-106178972-B | A kind of preparation method of high temperature resistant PPS gas separation membrane | 天津津纶新材料科技有限公司 | 2019-09-27 | — | — | CN | claimed |
| CN-108745007-A | A kind of preparation method of polyphenylene sulfide sulfone/polyphenylene sulfide composite membrane | 天津工业大学 | 2018-11-06 | — | — | CN | claimed |
| CN-1224333-A | Insecticide formulations | BAYER AG (DE) | 1999-07-28 | — | — | CN | claimed |
| CN-106178972-B | A kind of preparation method of high temperature resistant PPS gas separation membrane | 天津津纶新材料科技有限公司 | 2019-09-27 | — | — | CN | disclosed |
| CN-108745007-A | A kind of preparation method of polyphenylene sulfide sulfone/polyphenylene sulfide composite membrane | 天津工业大学 | 2018-11-06 | — | — | CN | disclosed |
| CN-106459361-A | Polymer dispersions containine acylmorpholines | 巴斯夫欧洲公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-100514510-C | High-performance all-solid-state lithium battery | IDEMITSU PETROCHEMICAL CO NAT (JP) | 2009-07-15 | — | — | CN | disclosed |
| CN-1116796-C | Insecticide formulations | BAYER AG (DE) | 2003-08-06 | — | — | CN | disclosed |
| US-6448286-B1 | PREFERENTIALLY INHIBITS OR MODULATES INDUCIBLE OVER CONSTITUTIVE ISOFORM OF NITRIC OXIDE SYNTHASE; SIDE EFFECT REDUCTION | G.D. SEARLE & CO. | 2002-09-10 | — | — | US | disclosed |
| US-6071906-A | INHIBITS OR MODULATES THE INDUCIBLE ISOFORM OF NITRIC OXIDE SYNTHASE OVER THE THE CONSTITUTIVE ISOFORMS; ANTIARTHRITIC, -DIABETIC, ISCHEMIC, THROMBOSIS AGENTS; CARDIOVASCULAR DISORDERS; TOXIC SHOCK SYNDROME; AUTOIMMUNE DISEASES | G. D. SEARLE & CO. (US) | 2000-06-06 | — | — | US | disclosed |
| US-6046211-A | TREATMENT OF ARTHRITIS OR INFLAMMATORY BOWEL DISEASE, CARDIOVASCULAR ISCHEMIA, DIABETES, HYPERALGESIA (ALLODYNIA), CEREBRAL ISCHEMIA AND OTHER CNS DISORDERS | G.D. SEARLE & CO. (US) | 2000-04-04 | — | — | US | disclosed |
| CN-1224333-A | Insecticide formulations | BAYER AG (DE) | 1999-07-28 | — | — | CN | disclosed |
| EP-0897912-A1 | Amidino derivatives useful as nitric oxide synthase inhibitors | G.D. SEARLE & CO. (US) | 1999-02-24 | — | — | EP | disclosed |
| US-5854234-A | Amidino dervatives useful as nitric oxide synthase inhibitors | G. D. SEARLE & CO. (US) | 1998-12-29 | — | — | US | disclosed |
| EP-0724570-A1 | AMIDINO DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | G.D. SEARLE & CO. (US) | 1996-08-07 | — | — | EP | disclosed |
| WO-1995011231-A1 | AMIDINO DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | G. D. SEARLE & CO. (US) | 1995-04-27 | — | — | WO | disclosed |