Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL798477 | 0.81 | MCHR1 (0.35) | — | |
| SCHEMBL7941806 | 0.80 | KCNH2 (0.34) | TGFBR1 | |
| SCHEMBL12248520 | 0.76 | NOS3 (0.32) | — | |
| SCHEMBL21664098 | 0.75 | — | — | |
| SCHEMBL31035602 | 0.75 | APP (0.31) | — | |
| SCHEMBL12778122 | 0.71 | EGLN2 (0.31) | — | |
| SCHEMBL20138203 | 0.71 | EGLN2 (0.34) | TGFBR1 | |
| SCHEMBL31035721 | 0.71 | — | — | |
| SCHEMBL4179744 | 0.70 | PTGS1 (0.37) | — | |
| SCHEMBL21663752 | 0.69 | ALDH1A3 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140235626-A1 | PYRIDINE DERIVATIVES AND A PHARMACEUTICAL COMPOSITION FOR INHIBITING BACE1 CONTAINING THEM | SHIONOGI & CO., LTD. (JP) | 2014-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140235626-A1 | PYRIDINE DERIVATIVES AND A PHARMACEUTICAL COMPOSITION FOR INHIBITING BACE1 CONTAINING THEM | BACE1, BACE2, APP | TGFBR1 544/4885PANK3 4835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.