SCHEMBL1596048

SCHEMBL1596048

O=S(=O)(Cl)c1ccc(CCl)cc1Cl

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TRPV4 Q9HBA0 4/20 0.50
CA2 P00918 3/20 0.34
CA1 P00915 2/20 0.34
CA7 P43166 1/20 0.34
CA9 Q16790 1/20 0.34
CA14 Q9ULX7 1/20 0.34
TTR P02766 2/20 0.33
IDO1 P14902 1/20 0.33
PTGES2 Q9H7Z7 2/20 0.33
GSTO1 P78417 1/20 0.33
CYP3A4 P08684 1/20 0.32
ADRA1D P25100 1/20 0.32
TSHR P16473 1/20 0.32
PNMT P11086 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1597797 0.82 TRPV4 (0.49) TRPV4CA2CA1CA7CA9
Hydrochloric Acid SCHEMBL27785609 0.81 TTR (0.35) TRPV4CA2CA1CA7CA9
SCHEMBL12570799 0.79 TRPV4 (0.46) TRPV4CA2CA1CA7PTGES2
SCHEMBL27704411 0.79 TRPV4 (0.46) TRPV4CA2CA1CA7CA9
SCHEMBL3242247 0.78 GSTO1 (0.53) TRPV4GSTO1TSHR
SCHEMBL7943228 0.78 TRPV4 (0.45) TRPV4CYP3A4ADRA1DTSHR
SCHEMBL2395680 0.77 TRPV4 (0.44) TRPV4CA2CA1ADRA1DTSHR
SCHEMBL2749113 0.77 SMN1; SMN2 (0.45) TRPV4CA2CA1CA7GSTO1
SCHEMBL29519358 0.74 TRPV4 (0.57) TRPV4CYP3A4TSHR
SCHEMBL444929 0.74 TRPV4 (0.57) TRPV4CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1780224-B1 MULTIBRANCHED POLYMERS AND PROCESS FOR PRODUCTION THEREOF NIPPON SODA CO (JP) 2015-02-18 EP disclosed
US-8710165-B2 Multibranched polymer and method for producing the same NIPPON SODA CO., LTD. (JP) 2014-04-29 US disclosed
CN-101001887-B Multi-branched polymer and method for producing same NIPPON SODA CO.,LTD. (JP) 2012-02-08 CN disclosed
US-20110152388-A1 Multibranched polymer and method for producing the same NIPPON SODA CO., LTD. (JP) 2011-06-23 US disclosed
US-7919570-B2 narrowly dispersed; controlled molecular weight; ionic conductivity, shape stability; battery adhesive or binder; 1,1,2,2-tetrakis(4-hydroxyphenyl)ethane or pentaerythritol reacted with bromoisobutyroyl bromide for core; living radical polymerization of acrylate or a styrene at halogen atoms as the arms NIPPON SODA CO., LTD. (JP) 2011-04-05 US disclosed
US-20080214685-A1 Multibrached Polymer and Method for Producing the Same NIPPON SODA CO., LTD. (JP) 2008-09-04 US disclosed
CN-101001887-A Multi-branched polymer and method for producing same NIPPON SODA CO (JP) 2007-07-18 CN disclosed
EP-1780224-A1 MULTIBRANCHED POLYMERS AND PROCESS FOR PRODUCTION THEREOF NIPPON SODA CO., LTD. (JP) 2007-05-02 EP disclosed