SCHEMBL1597797

SCHEMBL1597797

O=S(=O)(Cl)c1ccc(CBr)cc1Cl

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TRPV4 Q9HBA0 5/20 0.49
CYP4F2 P78329 1/20 0.38
CYP4A11 Q02928 1/20 0.38
CA2 P00918 2/20 0.36
CA1 P00915 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
CA14 Q9ULX7 1/20 0.36
IDO1 P14902 1/20 0.32
PTGES2 Q9H7Z7 2/20 0.32
GSTO1 P78417 1/20 0.32
ADRA1D P25100 1/20 0.32
CYP3A4 P08684 1/20 0.31
NMT1 P30419 1/20 0.31
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
SLC6A3 Q01959 1/20 0.31
PNMT P11086 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27704411 0.85 TRPV4 (0.46) TRPV4CA2CA1CA7CA9
SCHEMBL1013697 0.83 ADRA1D (0.44) CYP4F2CYP4A11CA2CA1CA7
SCHEMBL29595036 0.83 ADRA1D (0.44) CYP4F2CYP4A11CA2CA1CA7
SCHEMBL24051716 0.83 CA1 (0.44) CYP4F2CYP4A11CA2CA1CA7
SCHEMBL1596048 0.82 TRPV4 (0.50) TRPV4CA2CA1CA7CA9
Hydrochloric Acid SCHEMBL27763840 0.81 CYP4F2 (0.40) TRPV4CYP4F2CYP4A11CA2CA1
SCHEMBL24050330 0.79 TRPV4 (0.36) TRPV4CYP4F2CYP4A11CA2
SCHEMBL20488770 0.79 GSTO1 (0.51) TRPV4CYP4F2CYP4A11GSTO1
SCHEMBL12570799 0.78 TRPV4 (0.46) TRPV4CA2CA1CA7PTGES2
SCHEMBL7943228 0.77 TRPV4 (0.45) TRPV4ADRA1DCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1780224-B1 MULTIBRANCHED POLYMERS AND PROCESS FOR PRODUCTION THEREOF NIPPON SODA CO (JP) 2015-02-18 EP disclosed
US-8710165-B2 Multibranched polymer and method for producing the same NIPPON SODA CO., LTD. (JP) 2014-04-29 US disclosed
US-20110152388-A1 Multibranched polymer and method for producing the same NIPPON SODA CO., LTD. (JP) 2011-06-23 US disclosed
US-7919570-B2 narrowly dispersed; controlled molecular weight; ionic conductivity, shape stability; battery adhesive or binder; 1,1,2,2-tetrakis(4-hydroxyphenyl)ethane or pentaerythritol reacted with bromoisobutyroyl bromide for core; living radical polymerization of acrylate or a styrene at halogen atoms as the arms NIPPON SODA CO., LTD. (JP) 2011-04-05 US disclosed
CN-101593852-B Multibranched polymers and process for production thereof NIPPON SODA CO 2011-03-02 CN disclosed
CN-101593852-A Multibranched polymers and manufacture method thereof NIPPON SODA CO (JP) 2009-12-02 CN disclosed
US-20080214685-A1 Multibrached Polymer and Method for Producing the Same NIPPON SODA CO., LTD. (JP) 2008-09-04 US disclosed
EP-1780224-A1 MULTIBRANCHED POLYMERS AND PROCESS FOR PRODUCTION THEREOF NIPPON SODA CO., LTD. (JP) 2007-05-02 EP disclosed