SCHEMBL15960965

SCHEMBL15960965

Cc1ccc(Nc2ccc(C(C)(c3ccccc3)c3ccccc3)cc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.65
GAA P10253 3/20 0.50
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
ESR1 P03372 2/20 0.50
ESR2 Q92731 2/20 0.50
L3MBTL1 Q9Y468 4/20 0.49
NPC1 O15118 5/20 0.47
RAB9A P51151 5/20 0.47
ALDH1A1 P00352 2/20 0.46
MAPK1 P28482 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
TSHR P16473 2/20 0.46
HSD17B10 Q99714 2/20 0.46
ALOX15 P16050 1/20 0.46
ALOX12 P18054 1/20 0.46
PTGS1 P23219 1/20 0.46
SLC6A2 P23975 1/20 0.46
PTGS2 P35354 1/20 0.46
HTR2B P41595 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10951232 0.98 HPGD (0.68) HPGDGAAMEN1KMT2AESR1
SCHEMBL465381 0.92 ESR1 (0.58) HPGDGAAMEN1KMT2AESR1
SCHEMBL8207410 0.91 ESR1 (0.67) HPGDGAAMEN1KMT2AESR1
SCHEMBL14571901 0.88 HPGD (0.65) HPGDGAAMEN1KMT2AESR1
SCHEMBL19200980 0.87 ESR1 (0.62) HPGDMEN1KMT2AESR1ESR2
SCHEMBL8784133 0.87 ESR1 (0.62) HPGDMEN1KMT2AESR1ESR2
SCHEMBL10776423 0.86 HPGD (0.68) HPGDGAAMEN1KMT2AESR1
SCHEMBL10776351 0.81 HPGD (0.52) HPGDGAAMEN1KMT2AL3MBTL1
SCHEMBL12029052 0.81 ESR1 (0.56) HPGDMEN1KMT2AESR1ESR2
SCHEMBL24137168 0.80 HPGD (1.00) HPGDGAAMEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230333474-A1 RESIST UNDERLAYER FILM-FORMING COMPOSITION COMPRISING FLUOROALKYL GROUP-CONTAINING ORGANIC ACID OR SALT THEREOF NISSAN CHEMICAL CORPORATION (JP) 2023-10-19 US disclosed
US-9263286-B2 Diarylamine novolac resin NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2016-02-16 US disclosed
US-20140235059-A1 DIARYLAMINE NOVOLAC RESIN NISSAN CHEMICAL INDUSTRIES, LTD (JP) 2014-08-21 US disclosed